ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

摘要:

Researchers are closer to understanding the role of aspirin and NSAIDs in preventing colorectal cancer, according to the findings from several studies presented at Digestive Disease Week [San Diego, US; May 1995]. New analyses of data from the Polyp Prevention Study 1 (PPS 1) confirm that aspirin use reduces the recurrence of large bowel adenomas. However, the dosage of aspirin that may achieve this effect remains unknown. On a mechanistic note, data fromin vitrostudies and a study in patients with familial adenomatous polyposis (FAP) indicate that sulindac may cause adenoma regression by inducing apoptosis. In addition, the novel NSAID balsalazide, a prodrug of 5-aminosalicylic acid, has been shown to inhibit human cancer cell proliferationin vitro.

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

摘要:

Riluzole [Rilutek®; Rhône-Poulenc Rorer; phase III] is the first treatment for amyotrophic lateral sclerosis (ALS) to be associated with significant prolongation of survival, when compared with placebo in a randomised, double-blind trial. Efforts are underway to encourage local regulatory authorities around the world to make the drug available to patients with ALS as soon as possible. An analysis of the results of the phase III study were presented at the 47th Annual Meeting of the American Academy of Neurology [Seattle, US; May 1995].

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS