ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

摘要:

A conference organised by theLancetwas dedicated to examining recent progress in dementia research. Entitled ‘The Challenge of the Dementias’ [Edinburgh, Scotland; April 1996], the conference brought together experts in epidemiology, genetics, neuroimaging and drug treatment, to discuss today's issues. Their conclusions indicate that the greatest progress of recent years has been in the genetic field, with the discovery of the apolipoprotein E type 4 allele(APOE-&egr;4)and its link to an increased risk of late-onset Alzheimer's disease. A number of epidemiological findings have also been made, and diagnostic methods have benefited from several advances. However, apart from the development of tacrine and second-generation cholinesterase inhibitors, such as galantamine, there has been little progress in the drug treatment of this condition.

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

摘要:

Cytokine researchers, who have invested numerous years determining the role of cytokines in autoimmune disease, are now beginning to see the fruits of their work. There is optimism that cytokine antagonists will provide chondroprotective benefits to patients with rheumatoid arthritis, and clinical trials to test this are now underway. Also, research suggesting the existence of a number of genetic indicators has led researchers to investigate the feasibility of tailoring treatment to individual patients based on genotype information. Back in the laboratory, researchers are looking at reducing the expression of pro-inflammatory cytokines by inhibiting specific DNA-binding transcription factors. Each of these developments were featured at the 8th Asia-Pacific League of Associations for Rheumatology Congress [Melbourne, Australia; April 1996].

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS