摘要:

Abstract.The influence of extracellular fluid volume expansion on the plasma aldosterone concentration (PAC) was investigated in five anephric and six non‐nephrectomized patients on regular haemodialysis, and compared to a control group of four anephric and four non‐nephrectomized patients. Plasma‐renin activity, cortisol, Na+, and K+were measured together with the PAC during the investigation. In anephric patients the PAC remained constant during the control period as well as during extracellular fluid volume expansion by infusion of 350 mmol of 20% mannitol. In the non‐nephrectomized patients PAC diminished after mannitol infusion. The decline in PAC was correlated with the basal levels of PAC and the plasma renin activity. It is concluded that 5% extracellular fluid volume expansion has no direct influence on the regulation of PAC in patients without the renal renin‐angiotensin system and that the regulation of PAC in anephric patients in the present investigation is probably mediated by changes in potassium

ISSN:0014-2972    

DOI:10.1111/j.1365-2362.1977.tb01571.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Abstract.Organ blood flow was measured in eight spontaneously breathing male New Zealand white rabbits exposed to a 50 min period of asphyxia. The results were compared with eight control animals. Cardiac output and arterial pressure did not change. There was increased flow to the heart, brain and diaphragm. Flow to the kidneys and adipose tissue was reduced. Flow to the gastro‐intestinal tract, liver, skeletal muscle and carcass was unchanged. Prolonged moderate asphyxia produces preferential blood supply to vital organs and maintains flow to the skeletal musculature and the gastro‐intestinal tract; their blood supply is diverted mainly from the kidneys. These changes are similar to those seen in haemorrhagic and endotoxic shock in the rab

ISSN:0014-2972    

DOI:10.1111/j.1365-2362.1977.tb01572.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Abstract.Binding of zinc to macromolecules when added to serum was measured by ultrafiltration. At a final ratio of 0.6 mol zinc per mol albumin, zinc dissociable by glycine was significantly greater in diluted serum from patients with decompensated alcoholic cirrhosis than in normal serum samples similarly prepared. Low serum zinc concentrations, often observed in patients with alcoholic cirrhosis, may be related in part to a reduced affinity of plasma albumin for exchangeable zinc.

ISSN:0014-2972    

DOI:10.1111/j.1365-2362.1977.tb01573.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

ISSN:0014-2972    

DOI:10.1111/j.1365-2362.1977.tb01574.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

ISSN:0014-2972    

DOI:10.1111/j.1365-2362.1977.tb01575.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY