摘要:

Hypercholesterolemia has not been considered an important risk factor for stroke; however, statin therapy reduces stroke in coronary heart disease patients. Statins may provide cerebrovascular protection through various mechanisms that include a reduction in the incidence of embolic stroke from cardiac, aortic and carotid sites, stabilization of vulnerable carotid atherosclerotic plaque, and improvement in cerebral blood flow.

ISSN:1350-7540    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Brain arteriovenous malformations are currently attracting increasing attention among clinicians as modern brain imaging techniques facilitate both diagnostic and follow-up evaluation. Their frequent presentation in young individuals, at times with flagrant clinical effects caused by cerebral hemorrhages or seizure disorders, keeps clinicians alert to any improvement in treatment strategies. Recent technical advances in surgical, endovascular, and radiation therapy add to the constantly accumulating data on clinical features, natural course, and treatment outcome in adult arteriovenous malformation patients. This review focuses on new concepts in arteriovenous malformation etiology, classification, treatment, and study approaches.

ISSN:1350-7540    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Magnetic resonance imaging of patients with primary intracerebral haemorrhage has drawn attention to focal areas of signal loss, which were suggested to indicate hemosiderin deposition from earlier bleeds. Correlative histopathologic data have recently confirmed this assumption and support a strong association between the occurrence of microbleeds and various types of small vessel disease, such as hypertensive lipofibrohyalinosis and cerebral amyloid angiopathy. Therefore, microbleeds that are detectable by magnetic resonance imaging could be viewed as markers for vessel wall disorders with a higher tendency for intracerebral bleeding. This finding appears to be of diagnostic importance, but could also help to predict a patient's risk for spontaneous rebleeding or bleeding complications after anticoagulation.

ISSN:1350-7540    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

New magnetic resonance angiographic sequences using gadolinium infusion allow high-quality images of supra-aortic vessels. Raw data may be obtained in a short scan time of less than 30 s, with a large acquisition volume from the aortic arch to the circle of Willis. After computed reconstruction of the vascular tree, angiograms appear similar to those obtained with conventional catheter angiography. Parameters of the sequence must be carefully chosen, however, with trade-offs between spatial resolution, scan time, acquisition volume and contrast of image. New developments have been proposed to improve the image quality with different acquisition strategies. These recent advances will probably be useful to assess the carotid and the vertebral arteries with more accuracy. They will require high-performance gradient systems and sophisticated software that is not yet available on all machines, however.

ISSN:1350-7540    

出版商:OVID    

年代:2000

数据来源: OVID

ISSN:1350-7540    

出版商:OVID    

年代:2000

数据来源: OVID