ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID

ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID

ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID

ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

Bartonella henselae can cause cat scratch disease and bacillary angiomatosis, a multisystem disorder seen primarily in patients with the acquired immunodeficiency syndrome. Both of these diseases are associated with neurologic complications, particularly encephalopathy. B. henselae may also cause bacteremia and endocarditis, and has been associated with aseptic meningitis and with dementia in patients also infected with the human immunodeficiency virus. Recent advances in identification of this difficult-to-culture organism will lead to recognition of more neurologic complications.

ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

There have been important recent advances in the diagnosis of acute viral infections of the nervous system. Polymerase chain reaction amplification of nucleic acids in cerebrospinal fluid and tissues is a rapid and accurate tool in the diagnostic evaluation of patients with suspected infections. It has proved to be highly valuable in the noninvasive diagnosis of herpes simplex virus encephalitis and also in establishing the role of herpes simplex virus infection in Mollaret's meningitis. Improved diagnosis of herpesvirus infections should lead to more appropriate antiviral therapy and better outcomes.

ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

Three common opportunistic infections in patients with the human immunodeficiency virus are being more accurately diagnosed and effectively treated as a result of recent advances. Toxoplasmosis may be prevented in some cases, and can be recognized and treated noninvasively in most cases. Cryptococcal therapy has been enhanced by successful development of oral azole therapy. Cytomegalovirus encephalitis is now an entity that can be diagnosed antemortem, and thus efforts to treat it can now be evaluated.

ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

The human T lymphotropic virus, type-I is associated with a slowly progressive neurologic disorder termed human T lymphotropic virus, type-I associated myelopathyhropical spastic paraparesis. Considerable information on the pathology, epidemiology, virology, and immunology is known about this disorder and will serve as a framework to define the role that a human retrovirus can play in human disease. In particular, this review will discuss the role of cellular immune responses to the virus in patients with human T lymphotropic virus, type-I associated myelopathyhropical spastic paraparesis and how these responses may be associated with the pathogenesis of this disorder. By defining virus-specific functional cellular host responses we hope to improve our understanding of the underlying mechanisms that may be involved in the neuropathology of human T lymphotropic virus, type-I associated neurologic disease.

ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

Progressive multifocal leukoencephalopathy is a viral-induced demyelinating disease of the central nervous system usually occurring in the immuno-compromised individual. The incidence of progressive multifocal leukoencephalopathy has risen sharply over the past decade because of widespread human immunodeficiency virus infection leading to immunodeficiency. This increased incidence of progressive multifocal leukoencephalopathy may also be due to better recognition of its clinical signs, and more rapid and reliable laboratory diagnosis of JC virus, the etiologic agent. There have also been advances in the molecular detection of the JC virus and the identification of variations in the viral genome sequence that may affect its multiplication cycle in different tissues. Clinical and basic research have resulted in a better understanding of the pathogenesis of progressive multifocal leukoencephalopathy and have provided sufficient information to plan new approaches for treatment.

ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID

ISSN:1350-7540    

出版商:OVID    

年代:1995

数据来源: OVID