ISSN:8755-1039    

DOI:10.1002/dc.2840010302

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY

ISSN:8755-1039    

DOI:10.1002/dc.2840010303

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY

摘要:

AbstractThe goal of this investigation was to determine the practical role of cytopathology in the clinical and laboratory diagnosis of asbestos‐related pulmonary diseases. For this purpose, sputum, bronchial washings, lung tissues, and pleural fluids were obtained from asbestos workers and controls. The asbestos‐associated pulmonary diseases studied were: (1) asbestosis, (2) carcinoma, and (3) mesothelioma. The cytology smears were prepared with both Papanicolaou and iron stains. Lung tissues were digested by the Chlorox (5.25% sodium hypochlorite solution) technique for quantitation of asbestos bodies. Asbestos bodies within the sputum were found to be highly specific markers for past asbestos exposure, indicating a heavy residual pulmonary asbestos load (>900 asbestos bodies/g wet lung weight). Asbestos bodies in sputum were also found to have a highly significant relationship (P<0.001) with the degree of accompanying atypia of bronchial epithelial cells. Bronchial washings appeared to be more sensitive than sputum for the detection of asbestos bodies. Asbestos bodies were not found within the pleural fluids of malignant mesotheliomas. It is concluded that sputum cytology screening represents a practical, noninvasive, and inexpensive approach to the diagnosis and study of asbestos expos

ISSN:8755-1039    

DOI:10.1002/dc.2840010304

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY

摘要:

AbstractThe records of 134 patients who underwent bronchoscopy at the Forbes Health System hospitals between January 1, 1982 and December 31, 1983 were reviewed. The number of pre‐ and postbronchoscopy sputa obtained on each patient, final diagnosis, and follow‐up for 6 to 30 months were obtained. Tissue obtained at bronchoscopy yielded a diagnosis of malignancy in 71 of 84 (84.5%) patients who received that final diagnosis. Addition of postbronchoscopy sputa examination increased the yield to 73 of 84 (86.9%). Prebronchoscopy sputa contributed no diagnoses beyond those made by bronchoscopically obtained material. The cost to the patient of examining pre‐ and postbronchoscopy sputa in addition to bronchoscopically obtained cytologic and biopsy material is 70% higher than that of examining bronchoscopically obtained material alone. Indirect costs of increased hospital stay may also be significant. We propose early bronchoscopy without prebronchoscopy sputa in cases where there is clinical suspicion of lung cancer. Postbronchoscopy sputa should be obtained, but only processed for microscopic examination if the bronchoscopically obtained material does not yield a diag

ISSN:8755-1039    

DOI:10.1002/dc.2840010305

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY

摘要:

AbstractThis work is based on 15 years experience with more than 9000 needle aspiration biopsies from the breast performed by a number of clinicians without syringe guns. From 1981 through 1983, 329 carcinomas were detected with a sensitivity of 90%. A positive or suspicious report was issued in 17 of the 32 minimal carcinomas. There were no false‐positive diagnoses. A retrospective comparative study was made on the aspiration biopsy cytology specimens from 65 histologically verified carcinomas: 30 infiltrating ductal, 16 infiltrating lobular, 10 medullary, and 10 colloid carcinomas. Parameters included the pattern, major malignant criteria, and cell measurements by calibrated ocular micrometry. The classic features of each carcinoma and the differential cytomorphology are describe

ISSN:8755-1039    

DOI:10.1002/dc.2840010306

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY

摘要:

AbstractSix cases of gastric remnant cancer that occurred many years after Billroth II gastrectomy and gastrojejunostomy for benign disease are reported. They are classified as intestinal type and gastric type on the basis of their morphologic appearance. Their cytologic and histologic features are tabulated along with a summary of the clinical histories. Emphasis is placed on the possible high risk for patients with Billroth II procedures of developing cancer 10 to 25 years after surgery. Endoscopic follow‐up including cytologic study is essential to diagnose gastric remnant cancer in its early stage to secure a better prognosi

ISSN:8755-1039    

DOI:10.1002/dc.2840010307

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY

摘要:

AbstractThe fine needle aspiration cytology of two cases of bronchiolo‐alveolar cell carcinoma of the lung having unusual features is reported. One case demonstrated numerous psammoma bodies in the cytologic smears, whereas the other case showed an abundance of cells with optically clear nuclei. Both peripherally located tumors were resected and confirmed as primary bronchiolo‐alveolar cell carcinoma by histologic and ultra‐structural examination. We believe this to be the first report describing these unusual features of bronchiolo‐alveolar cell carcinoma diagnosed by fine needle aspiration cytology. Presented is a discussion of psammoma bodies and optically clear nuclei seen in primary and metastatic tumors of the lung. This will aid in the diagnosis of these cases. Diagn Cytopathol 1985;1

ISSN:8755-1039    

DOI:10.1002/dc.2840010308

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY

摘要:

AbstractMalacoplakia, a rare form of chronic granulomatous inflammation, most frequently involves the urinary tract of middleaged women. The disease represents an unusual inflammatory response to bacteria, most commonly Escherichia coli, and probably reflects some dysfunction in the immune system of the host. We describe two cases of malacoplakia involving in one patient the vagina and in the other the perianal subcutaneous tissue and lung. In both cases, the diagnosis was made concurrently by cytology and histologic examination of tissue sections. This, in turn, led to the institution of appropriate therapy with complete resolution of the disease. In smears, the characteristic von Hansemann histiocytes are larger than alveolar macrophages. They have a reticulated granular cytoplasm that is caused by excessive accumulation of lysosomal bodies, some of which upon mineralization give rise to the pathognomonic Michaelis‐Gutmann body. The latter, which is usually intracel‐lular, can be distinguished readily from psammoma bodies and should not be confused with yeasts. Diagn Cytopathol 1985;1:216

ISSN:8755-1039    

DOI:10.1002/dc.2840010309

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY

摘要:

AbstractSarcomas, excluding lymphomas, are relatively uncommon targets of transthoracic fine needle aspiration. This paper presents a series of 11 adult patients with a variety ofhistologically documented sarcomas that were positive on transthoracic fine needle aspiration. Most tumors were metastatic from extrathoracic primary sites. We summarize the cytologic appearances of the aspirates and the clinical roles of fine needle aspiration in this setting. The aspirates resembled the corresponding histologic sections in cellular morphology. Nine different histologic types of sarcomas therefore produced a wide variety of cytologic appearances. Two findings, though not specific for sarcomas, were common and are suggested as clues to the recognition of sarcomas: (1) poor cohesion of cells and (2) numerous spindle cells. Transthoracic fine needle aspiration confirmed a strongly suspected clinical diagnosis in 7 cases, and it clarified a more obscure clinical diagnosis in 4 cases. Suggestions are presented for differential diagnosis. Diagn Cytopathol 1985;1:221–

ISSN:8755-1039    

DOI:10.1002/dc.2840010310

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY

摘要:

AbstractCilia identifiable by light microscopy occur extremely rarely in malignant tumor cells. This report documents the presence of cilia on exfoliated malignant tumor cells shed from an ovarian adenocarcinoma. Cilia‐bearing tumor cells were observed in abdominal and pleural fluids. These cilia occurred at atypical locations. They were observed as unipolar, bipolar, lateral, and pericellular structures. Diagnostic features and implications of cilia in relation to malignant cells are discusse

ISSN:8755-1039    

DOI:10.1002/dc.2840010311

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1985

数据来源: WILEY