摘要:

The isolation and production of growth factors and the observation that a platelet extract will promote wound healing in chronic wounds has led to an interest in the study of growth factors and wound healing. We wished to study the effect of platelet-derived growth factor on wound contraction. However, because studies of growth factors and wound contraction are quite recent, we could find only two models described in the literature and neither seemed ideal. Both used small wounds, which are difficult to measure, anesthetics with slow induction and recovery and which are difficult to titrate, and no dressings, which permits the animals to lick the wounds and possibly introduce other growth factors.We therefore reviewed wound contraction models used for other studies. In particular, we reviewed the animal used, anesthetic, wound size and shape, dressing methods, scab treatment, and measurement and comparison techniques. We then combined features of many of them into a model that solves the problems listed and permits the study of topically applied growth factors and wound contraction. The composite model to be described uses a large, circular wound on the rat, halothane anesthesia, and flexible, Tubigrip dressings.

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

The use of occlusive taping following phenol chemical peel has become a standard technique. Many studies have demonstrated the effectiveness of tape occlusion in producing a deeper, more profound chemical peel.For the last 18 months, we have abandoned tape occlusion following phenol peel and have substituted an occlusive dressing using a thick layer of petroleum jelly (Vaseline). The occlusiveness provided by the petroleum jelly has proved to be almost as effective as the standard tape mask, and the results using this technique parallel those with a tape mask. The advantages of Vaseline occlusive dressing include greater patient comfort, the ability to evaluate the wound beneath the petroleum jelly, and the prevention of streaking, which can occur from uneven tape application. Eschar formation and crust separation are avoided after the peel by the constant use of facial lubricants, our preference being A & D ointment.

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

Seven free scapular fascial flaps with a skin graft on top were used to cover soft tissue defects of the hand and foot in 6 patients during the past two years. The size of the flap ranged from 7 × 8 cm to 8 × 12 cm. All flaps survived well, but one had partial loss as a result of infection. The advantages, disadvantages, indications, and important technical points of the surgery are discussed.

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

Lymphedema of the extremities is well documented in the literature. We present a case of lymphedema involving the face of a 27-year-old man and discuss the clinical presentation, microscopic findings, and surgical treatment. To our knowledge, this is the first such case report in the literature.

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID

ISSN:0148-7043    

出版商:OVID    

年代:1989

数据来源: OVID