|
11. |
Spectres RMN-13C DE β-Aminoalcools Derives DE L'Ephedrine ET De Leurs Oxazolidines |
|
Analytical Letters,
Volume 12,
Issue 6,
1979,
Page 641-655
M. Baudet,
M. Gelbcke,
G. Lagrange,
Preview
|
PDF (527KB)
|
|
摘要:
The carbon-13 NMR spectra of β-aminoalcohols related to nor-and pseudonor-ephedrine (N-CH3; N-C2H5; N-iC3H7; N-tC4H9) and the series of the corresponding oxazolidines from formaldehyde and benzaldehyde were obtained and dicussed. The configuration of the 3-alkyl-2, 5-diphenyl-4-methyloxazolidines was established.
ISSN:0003-2719
DOI:10.1080/00032717908055715
出版商:Taylor & Francis Group
年代:1979
数据来源: Taylor
|
12. |
Specific and Sensitive High Performance Liquid Chromatographic Determination of Alprazolam or Triazolam |
|
Analytical Letters,
Volume 12,
Issue 6,
1979,
Page 657-671
WadeJ. Adams,
Preview
|
PDF (429KB)
|
|
摘要:
A specific and highly sensitive liquid chromatographic procedure has been developed for the rapid determination of intact alprazolam or triazolam in dog serum, using these structurally similar triazolobenzodiazepines as mutual internal standards. The procedure consists of (1) extracting one ml of alkali buffered serum with toluene, (2) evaporating an aliquot of the toluene to dryness, and (3) quantitating the redissolved residue by HPLC using ultraviolet detection (221 nm). Samples were chromatographed on a microparticulate reverse phase column using a mobile phase composed of acetonitrile: isopropanol: water (94:5:1) and a flow rate of 0.75 ml/min. Metabolites of alprazolam and triazolam did not interfere in the assay. The lower limit of detection was approximately 1 ng/ml of serum extracted. The utility of the analytical methodology for the determination of alprazolam or triazolam in pharmacokinetic studies in the dog was demonstrated.
ISSN:0003-2719
DOI:10.1080/00032717908055716
出版商:Taylor & Francis Group
年代:1979
数据来源: Taylor
|
13. |
Editorial board page for “Analytical Letters”, Volume 12, Number 6 |
|
Analytical Letters,
Volume 12,
Issue 6,
1979,
Page -
Preview
|
PDF (92KB)
|
|
摘要:
This is a scanned image of the original Editorial Board page(s) for this issue.
ISSN:0003-2719
DOI:10.1080/00032717908055704
出版商:Taylor & Francis Group
年代:1979
数据来源: Taylor
|
|