摘要:

A new spectrophotometric method was developed for the assay of 0–6 mg/1 of iron (II) in a number of certified Iraqi drugs. The Sandell index is 0.07 μg cm2-and the ε max is 6000 1 mol−1cm−1. An interference study is also described.

ISSN:0003-2719    

DOI:10.1080/00032718708082599

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

摘要:

The stopped-flow technique is used to develop fluorimetric determinative methods for two phenothiazine drugs: perphenazine and chlorpromazine. The methods are based on the oxidation of these compounds to their corresponding fluorescent sulfoxides. Owing to the intrinsic characteristics of this technique, which allow rapid and thorough mixing of reactants, the oxidation is affected by dissolved oxygen itself, which therefore makes an oxidizing reagent unnecessary. Two methods are proposed for each phenothiazine, one based on initial rate and another on maximum fluorescence intensity measurements. Their linear ranges are 0.1–40 μg mL−1and their precision (%RSD) between 0.9 and 2.8%. These methods have been satisfactorily applied to the determination of both phenothiazines in several pharmaceutical preparations. On the basis of the additivity of the initial rate and maximum fluorescence intensity of perphenazine and chlorpromazine, the proportional equations principle is applied to the simultaneous determination of these compounds. Perphenazine/chlorpromazine mixtures in ratios between 1:8 and 8:1 are successfully resolved.

ISSN:0003-2719    

DOI:10.1080/00032718708082600

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

摘要:

Spectrophotometric and electrochemical properties of sulmazole are studied. The acid-base constants are calculated (pka1= 3.88 ± 0.04 and pKa2= 11.39 ± 0.06).

ISSN:0003-2719    

DOI:10.1080/00032718708082601

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

摘要:

A colorimetric method for the determination of tetracycline and oxytetracycline is developed. It depends on nitration and reaction of the nitroderivatives with acetone in the presence of potassium hydroxide. A highly colored complex is produced. Variables such as temperature) time of heating, volume of nitrating mixture, acetone and potassium hydroxide have been evaluated to permit the selection of the most advantageous technique. Beer's Law is obeyed over the concentration range from 0.004 – 0.04 mg ml for tetracycline and oxytetracycline.

ISSN:0003-2719    

DOI:10.1080/00032718708082602

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

摘要:

This is a scanned image of the original Editorial Board page(s) for this issue.

ISSN:0003-2719    

DOI:10.1080/00032718708082588

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor