摘要:

A new potentiometric method is developed for determination of 10–100 μg ml of L-ascorbic acid in pure solution and Pharmaceuticals with 0.1 to 0.8% RSD.

ISSN:0003-2719    

DOI:10.1080/00032718708067994

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

摘要:

Clidinium bromide is a quaternary ammonium anticholinergic agent with peripheral effects. It is commercially available in combination with chlordiazepoxide. There is no official compendial method available for the analysis of both compounds concurrently. Conventional methods for determining both compounds involve extensive extraction and thus are time-consuming, and lack precision. The analytical scheme described in this paper provides a fast and reliable reverse-phase HPLC for chlordiazepoxide and clidinium bromide in pharmaceutical combinations. The mobile phase was 0.04 M ammonium acetate in 70% acetonitrile solution with 1% dimethylformamide (pH 6). The column was microPak MCH-10 (300.0 mm × 4.0 mm), UV detection at 254 nm and benzophenone was used as internal standard. The method was confirmed for linearity, recovery, specificity, accuracy, and applicability.

ISSN:0003-2719    

DOI:10.1080/00032718708067995

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

摘要:

This is a scanned image of the original Editorial Board page(s) for this issue.

ISSN:0003-2719    

DOI:10.1080/00032718708067983

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor