摘要:

Reactive epoxides, formed as intermediates in the enzymic hydroxylation of olefinic compounds, can be trapped by their reaction with trimethylchlorosilane and detected by gas chromatography and combined gas chromatography-mass spectrometry as the trimethylsilyl derivatives of their chlorohydrin adducts. Mass spectrometric identification of the products is facilitated by the characteristic isotope ratio of chlorine. By using these derivatives, epoxides have been detected as intermediates in the metabolic conversion in the rat of allylic barbiturates to their corresponding glycols.

ISSN:0003-2719    

DOI:10.1080/00032717208064356

出版商:Taylor & Francis Group    

年代:1972

数据来源: Taylor

摘要:

In this day and age it is not an easy task to describe in a few pages the current status of any scientific discipline. This is particularly difficult if one deals with a n area such as analytical chemistry in France which is on the upswing. The present wirteup is focused on developments in French universities since the war: we shall not deal with analytical chemistry in industry, even though chemical companies and the French Atomic Energy Commission have had a paramount influence on recent developments. Indeed, French analytical chemists are being educated mainly to serve the needs of industrial laboratories.

ISSN:0003-2719    

DOI:10.1080/00032717208064345

出版商:Taylor & Francis Group    

年代:1972

数据来源: Taylor