ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID

摘要:

The English language literature that addresses the relationship between acetylation phenotype and clinical response to monoamine oxidase inhibitors is reviewed. In all, seven studies have been published in the last 20 years. Historical antecedents leading to interest in the relationship between acetylation phenotype and monoamine oxidase inhibitors are examined. Each study is then summarized, with comments about its relative merits and deficiencies. The review concludes that the data published do not support the notion of a correlation between acetylation phenotype and clinical response to monoamine oxidase inhibitors.

ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID

摘要:

The necessity for and efficacy of the anticonvulsant regimens are undisputed. However, inasmuch as epileptic patients are prone to psychiatric disorders, neurologists, psychiatrists, and others working with epileptic patients need to be aware of the role that anticonvulsant regimens may play in causing or exacerbating psychiatric disorders. Additionally, some of the anticonvulsants are thought to have potent positive psychotropic effects. The current literature on this important bio-psychosocial topic is reviewed with the purpose of suggesting helpful clinical and research approaches to patients treated by such methods.

ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID

摘要:

Clearances calculated from single oral dose data have been utilized to predict steady state levels of desipramine in 12 noninstitutionalized depressed elderly patients. Observed steady state plasma levels correlated very well (r = 0.967, p <0.0005) with those predicted from single dose clearances, but not with plasma levels obtained 20 hours after a single oral dose (r = 0.24,p > 0.2). The mean half-life of desipramine (20.9 hours) in this group of elderly (mean age, 72 years) was considerably less than values of “apparent disappearance” half-life previously reported for elderly patients receiving imipramine. The single dose clearance technique yielded a precise criterion for quantitating early compliance with and adjusting drug dosing regimens.

ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID

摘要:

This article reviews clinical reports of dermatological reactions to lithium. Such reactions include maculopapular, acneiform, and follicular eruptions, psoriasis, and other manifestations. Standard psychiatric texts offer the psychiatrist little information concerning the prevalence or seriousness of these reactions, nor do they discuss the effectiveness of various treatment alternatives. More surprisingly, most dermatology texts do not even describe skin reactions to lithium. Dermatological reactions to lithium may occur more commonly than previously documented, but with the exception of some psoriatic cases, management without the need for lithium discontinuation is usually possible.

ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID

ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID

ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID

ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID

ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID

ISSN:0271-0749    

出版商:OVID    

年代:1982

数据来源: OVID