摘要:

A cohort of 2,671 men, 1561 of whom were exposed to methyl methacrylate, was observed from 1951 to 1983 for mortality. This cohort consisted of men from two plants. This study utilizes detailed exposure estimates and smoking status to evaluate mortality patterns. We find no statistically significant excess all-cause or cause-specific mortality. Analysis of dose of methyl methacrylate with several cancer sites showed no trend. Men exposed to high levels of methyl methacrylate had cancer rates similar to those for men not exposed in the workplace, as well as for other men in the US population. An earlier epidemiology study reported a significant excess of colorectal cancer among persons exposed to several substances including methyl methacrylate. Our study results and results from animal studies do not support the hypothesis that methyl methacrylate is a human carcinogen.

ISSN:0096-1736    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

The determination of urinary N-monomethylacetamide (MMAO) in the end-of-shift urine sample was used to monitor exposure to dimethylacetamide (DMAC). Five workers were observed followed for 4 consecutive weeks. Airborne DMAC appeared to account for the greatest amount of urinary MMAO detected and, at the exposure concentrations encountered (0.5 to 2 ppm), a relationship of 10 ppm urinary MMAO for each 1 ppm DMAO inhaled was observed. Interindividual variation was small and no evidence of build-up in MMAO urinary levels was seen in these subjects. Mean airborne DMAO concentrations were somewhat higher by the end of the week, but the magnitude was such that the differences were not statistically significant. It is concluded that changes in DMAO exposures can be Quantitatively reflected by urinary MMAO.

ISSN:0096-1736    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

Dizziness, headaches, and weakness occurred among three men after short-term hydrocarbon exposure during improper welding procedures in a closed container. Symptoms were related to objective evidence of vestibular and cognitive dysfunction. Symptoms and abnormal test results persisted for 6 to 18 months. Simulation of the accident failed to demonstrate likely exposures except aliphatic hydrocarbons, well within the permissible exposure levels. Short-term exposures to neurotoxins may lead to long-term central nervous system abnormalities.

ISSN:0096-1736    

出版商:OVID    

年代:1989

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1989

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1989

数据来源: OVID