ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

A follow-up report was done of workers exposed to 42-dibromo-3-chloropropane (DBCP) 7 years after termination of exposure. A 1977 study of male pesticide workers exposed to DBCP in a California agricultural chemical plant identified many who were azoospermic or oligospermic. Sperm concentration and serum follicle-stimulating hormone (FSH) levels in 44 of these workers were reassessed 6 to 8 years after exposure was terminated in 1977. Two of the eight originally azoospermic workers produced sperm during the follow-up, although only one had normal sperm counts. No increase in sperm production could be detected in men who had low sperm counts in 1977, and elevated serum FSH levels did not drop in oligospermic or azoospermic men. These results suggest that permanent destruction of germinal epithelium occurs in most DBCP-sterile persons.

ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID

ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

A cross-sectional study has been carried out at The National Institutes of Health to examine the prevalence of laboratory animal allergy (LAA) in a population exposed to animals, and to compare the prevalence of general allergy in the exposedva control group. A group of 289 workers with light-to-moderate exposure to animals, 260 with heavy exposure, and 243 control subjects were interviewed.A slightly greater prevalence of general allergy was found among those working with laboratory animals (39%), than in the control group (33.9%), but the difference was not statistically signihnt.The prevalence of LAA in the total exposed group was 23.9%. A history of atopic problems and history of allergy to domestic animals correlated significantly with LAA, as did the number of species of animals handled and the average number of hoursper week exposed to laboratory animals, with evidence of dose-response relationships.

ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

Employers at laboratory animal facilities have begun to use selection criteria which proscribe employment of persons thought to be at increased risk of developing allergy to laboratory animals. Some of these criteria are: a personal history of allergy, chronic rhinitis, or asthma, positive direct skin tests, elevated serum immunoglobulin E, abnormal forced expiratory volume in 1 second, and a family history of allergy. The usefulness of these criteria were examined in preemployment screening when applied to job applicants who will be handling laboratory animals, by calculating the sensitivity, specificity, and positive predictive value (PPV) of each criterion. Results illustrated that the primary goal of the screening program must be determined before an evaluation can be made of the usefulness of potential screening criteria in meeting the goal, ie, to identify persons who are themselves at high risk (high PPV), to identify a large proportion of low-risk job applicants (specificity), or to screen out a large proportion of occupational disease (high sensitivity), because it is not possible to maximize these parameters simultaneously. Results indicate that, currently, the use of these screening criteria as determinants for hiring persons to work with laboratory animals is unwarranted.

ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

Most health professionals accept life-style as being causally related to morbidity and mortality, but many managers question this relationship, particularily in relation to corporate health care costs. This research compared responses from a lifestyle questionnaire (HealthScore), age, and organizational size, with Blue Cross/Blue Shield rates for eight work sites in Ohio. HealthScore was demonstrated to be the best predictor of health insurance rates. This relationship held for a secondary analysis involving Blue Shield rates acljusted for company size and coverage.

ISSN:0096-1736    

出版商:OVID    

年代:1986

数据来源: OVID