摘要:

A 23‐year‐old man suffering from sero‐negative rheumatoid arthritis developed severe penicillamine‐induced mouth ulcerations and erythematous maeules. Immunohistochemical staining in a biopsy specimen from the affected lingual mueosa showed substantial deposition of IgM and C3 in vessel walls below the necrotic epithelium. In the affected skin, irregular granular staining for IgG and IgM along the epidermal basement membrane zone was noted, and granular deposits of IgM were present in small vessels of dermal papillae. The mouth ulcerations healed promptly after withdrawal of the drug, whereas the macules persisted for some months. The immunohistochemical findings indicated that the drug eruptions were related to a vasculitis induced by deposition of immune co

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00155.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

In order to obtain information about the chemical reactivity of localized areas within natural enamel caries, thin ground sections prepared from white spot lesions were subjected to MCI solutions with 0.01, 0.05, and 0.1 N concentrations. Microradiographic examination combined by densitometric analysis demonstrated that the surface layer covering demineralized lesions remained relatively stable against acid attacks and that, despite the original lower degree of mineralization, its microradiographic density became higher than that of the underlying normal enamel during acid‐dissolution. Another interesting finding was that in the experiment using the most diluted HCI solution, a radiopaque zone became noticeable at the advancing front of the lesions in the course of dissolution. X‐ray microbeam diffraction analysis of these sections showed that no apparent alterations occurred in mineral structure of enamel with acid dissolution, except for the decrease in crystallinity of enamel apatite. Based on the results obtained here, one can expect that the surface layer and the interior part of natural carious lesions possess a high degree of resistance to acid attacks, relative to the underlying normal ena

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00156.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

The present study aims to obtain further information about the crystallographic and structural alterations in the mineral phase of enamel with the onset of caries. For this purpose, X‐ray microbeam diffraction analysis was carried out on ground sections prepared from natural while spot lesions. Electron spin resonance (ESR) analysis was also performed on block samples cut from white spot lesions and from undamaged enamel of the same teeth. The results of crystallinity measurements showed that enamel apatite in demineralized lesions was lower in crystallinity than the apatite in the surface layer and surrounding sound enamel. This X‐ray diffraction study also revealed the presence of two non‐apatitic minerals in the de‐mineralized lesions. One type of the mineral is whitlockite, giving spotty rings. The nature of the other mineral, giving a single ring‐like reflection, remains to be elucidated. A comparison of ESR spectra taken from the caries‐attacked and undamaged enamel provided evidence that the former samples have a lower degree of alignment of apatite microcrystals. The occurrence of non‐apatitic mineral phases and the observed difference in microcrystalline alignment may be the results of a remineraliz

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00157.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Thymidine kinase activity was assayed in scrum from 30 patients with oral squamous cell carcinoma and 30 controls. Thymidine kinase activity was significantly greater in patients with oral cancer than in controls and might be useful as a marker enzyme.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00158.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Nine cases of oral extranodal lymphomas arc described. Histologically, ft cases were histiocytic, 2 lymphocytic and I Burkitt's lymphoma. According to the criteria of the Japanese Lymphoma Study Group, 8 cases seemingly belonged to the B‐cell lymphoma classification, and one was unclassified. Geographical differences in the distribution of oral extranodal lymphomas between Japan and western countries were surveyed. A review of our cases and those in the literature revealed no significant difference in sex, age, frequency of B‐cell lymphomas or site of predilection. In Japan, histiocytic lymphomas were the most common type of extranodal oral lymphomas. The most prevalent type of oral extranodal lymphomas in western countries could not be determined from the literat

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00159.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Dark basal keratinocytes, characterized by a strong affinity for basic dyes and by electron density of cytoplasm and nucleus, could be recognized in eleven oral leukoplakias. The percentage of dark cells was higher in the group comprising leukoplakias verrucosa, and erosiva (28% of the basal cells) than in the leukoplakia simplex group (10%). The presence of these cells is a good indicator of the degree of histological dysplasia and correlates well with the preneoplastic potential of these lesions.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00160.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

The incidence and distribution of amyloid deposits in aged tongues obtained from 107 necropsies over 60 years of age were examined. Thirty‐nine tongues were affected with amyloid deposits and the overall incidence was 36.4%. The incidence increased with each advancing decade, and the group over 90 years old showed the higest incidence of 59.6%. Although the amount of amyloid deposits differed in each case, severely affected cases were most frequently found in the advanced decades. Amyloid deposits were almost always confined to blood vessels, especially arterioles and arteries. They occasionally occupied the entire wall and occluded the lumen. Blood vessels affected with amyloid were usually located in the muscle layers of the tongue. Vessels in the subepithelial layer and lingual glands were, however, sometimes affected. Amyloid deposits were resistant to Congo red staining with the potassium permangante method, and stained positively with DMAS. The present study suggested that the tongue is an important organ as to the appearance of amyloid deposits in elderly person

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00161.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Some clinical and histological characteristics of 23 oral carcinomas in the anterior vestibulum of snuff dipping Swedish males with an average age of 76 years were investigated. Examples of verrucous carcinomas as well as of ordinary, usually verrucoid but also ulcerating, squamous cell carcinomas were encountered. Widespread oral leukoplakia and second primary carcinoma–oral or other–was present in 5 and 6 cases respectively, and occurred together in 3 of these. Eleven cases out of 19 available for additional sectioning and staining showed candidal infect

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00162.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Irradiation of the major salivary glands of monkeys (Macaca mulatta) led cariogenic diets leads to caries clinically indistinguishable from radiation caries in man. This study compares the organic compostion of individual samples of plaque fluid and saliva from irradiated and control monkeys receiving the same cariogenic diet. Plaque and saliva were collected from lasting, tranquillised animals. Four irradiated animals were sampled repeatedly as were non‐irradiated controls. Total protein, albumin, immunoglobulins A, G, and M, and the third component of complement (C′3) were quantitated in plaque fluid and whole saliva. Salivary amylase and peroxidase activities were also determined. Plaque fluid and saliva samples were also subjected to polyacrylamide gel electrophoresis. The total viable anaerobic count and numbers ofStreptococcus mutanswere determined in samples of plaque. The results suggest that the major effect of irradiation leading to increased numbers ofS. mutansand caries susceptibility is in the amount, and not the composition, of the saliva produced by the residual gland tissue. The scanty flow of saliva may reduce the effectiveness of cleansing, buffering and lubrication mechanisms as well as resulting in a marked reduction in the total amount of specific and non‐specific immune factors entering the

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00163.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Books reviewed in this article:Principles and Techniques of Electron Microscopy Biological Application.M. A. HayatAnimal Models in Cariology, J.M. Tanzer, ed.Killey's Fractures of the Middle Third of the Facial Skelton, Peter banks 4th end.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1982.tb00164.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY