摘要:

Abstract.Natural, humoral and cellular immune mechanisms have all been implicated in the pathogenesis of chronic inflammatory periodontal disease. However, confusion still exists as to the role played by each of these immunological mechanisms. Recently, characterization of the cell types within the progressive lesion has been established, in which four recognizable zones were described.Immediately subjacent to the epithelium lining the periodontal pocket both polymorphonuclear leukocytes (PMN's) and macrophages were seen, while cells deeper in the tissues had the morphological appearance of lymphocytes. The majority of these lymphocytes had a B‐cell phenotype although a few T‐cells and macrophages were found. On the advancing front of the lesion the cells had the morphological appearance of plasma cells, the majority of which contained IgG. Other cells found in this region had the morphology of plasma cells yet contained no cytoplasmic immunoglobulin, but they did contain substantial amounts of lysosomal enzymes. Similar cells have previously been described in periodontal disease; their frequent association with fibroblasts may suggest that they are important in the pathogenesis. Deposits of IgG and fibrin were found in the fibrous tissue band surrounding the lesion. These results are reviewed and, although the zones described were not anatomically distinct, by describing the lesion in this way it was possible to establish a convenient model to explain the immunopathogenesis of progressive chronic inflammatory periodontal disease. In this respect, progressive chronic inflammatory periodontal disease in man should be considered as a B‐cell l

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1979.tb01826.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.A case is presented in which electron microscopy proved invaluable in determining the nature of a clinically innocuous lesion of the buccal mucosa. The clinical, histologic and ultrastructural features of the neoplasm identified are reviewed in the light of previous literature.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1979.tb01827.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.A case of odontogenic fibromyxoma of over 5 years’ duration which was evident roentgenographically (but not diagnosed) at the time of treatment for a fractured zygoma of the ipsilateral side is presented. The rate of growth did not appear to be significantly altered by trauma. The tumor was successfully treated by enucleation and curettage with removal of the associated teeth. No evidence of recurrence was noted 6 months postoperativel

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1979.tb01828.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Electron microscopic examination of tissue from a twice recurrent ameloblastic fibroma revealed the presence of intracellular collagen fibres in fibroblasts active in protein synthesis. The intracellular fibres were morphologically identical to collagen fibres located extracellularly. The literature on intracellular collagen in biological systems and pathological states has been reviewed, and attention is focussed on collagen phagocytosis and degradation by fibroblasts which are currently considered to represent the basis of connective tissue remodelling and turnover.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1979.tb01829.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.The mineral composition of 38 human salivary gland stones was described qualitatively on the basis of X‐ray diffraction and chemical analyses. In 32 submandibular stones, hydroxyapatite was the most frequently observed phase with a magnesium‐substituted whitlockite co‐phase (octacalcium phosphate was rarely present). In six parotid gland stones, apatite, magnesium substituted whitlockite and octacalcium phosphate were noted to be the major crystalline phases. Brushite was rarely found in either submandibular or parotid stones. This is the first report of octacalcium phosphate in salivary gland stones. All stones had ash weights ranging from 75–80%, but their Ca/P ratios could not be used to predict the crystalline phases present. Whitlockite was observed more frequently in the central regions of the submandibular stones than in the outer crusts. Possible explanations for the presence of each of these phases are di

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1979.tb01830.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Within 1 h after ligation of the main excretory duct of the rat submandibular salivary gland neutrophils begin to migrate into the parenchymal epithelium and by 18 h they accumulate, unchanged, within the lumina of acini and intralobular ducts. By 24 h, monocytes become the predominant in‐traepithelial migrating cell type. These selectively migrate into lumina of convoluted ducts where they phagocytize intraluminal material consisting of secretion products, egested cell debris and neutrophils. By 4 days monocytes laden with phagosomes begin to migrate into the stroma and by. 17 days relatively few leukocytes remain within the parenchyma. Changes in ligated gland weight reflect the cytological changes. It is concluded that in experimental obstructive adenitis monocytes play a most important role while neutrophils are adventitiou

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1979.tb01831.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Book reviews in this article:Mechanisms of Localized Bone Loss, eds. John E. Horton, Thomas M. Tarpley&William F. Davis.The Cranium of the Newborn Infant: An Atlas of Tomography and Anatomical Sections, by Robert H. Pierce, Michael W. Mainen&James F. Bosma.Clinical Outline of Oral Pathology: Diagnosis and Treatment, by Lewis R. Eversole.1978 Year Book of Dentistry, eds. M. L. Hale, S. P. Hazen, R. E. Moyers, D. F. Redig, H.B. G. Robinson&S. I. Silverman.Gingivitis, 2nd edn., by W. G. Cross.Sweeteners and Dental Caries, eds. James H. Shaw&Gerassimos G. Roussos.Methods of Caries Prediction, eds. Basil G. Bibby&Roald J. Shern.Self Assessment Manual # 1. Oral Surgery and Pathology, Bertram Cohen, David Mason&David Poswillo.Skin Manifestations in Visceral Cancer, Vladimir C. Andreev.Application of the International Classification of Diseases to Dentistry and Stomatology (ICD‐DA).Preventive Dentistry, Leon M. Silverstone.Color Atlas of Periodontology, J. Dermot Strahan&Ian M. Wait

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1979.tb01832.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1979.tb01833.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY