摘要:

AbstractLesions of the oral mucosa associated with wearing of removable dentures may represent acute or chronic reactions to microbial denture plaque, a reaction to constituents of the denture base material, or a mechanical denture injury. The lesions constitute a heterogeneous group with regard to pathogenensis. They include denture stomatitis, angular cheilitis, traumatic ulcers, denture irritation hyperplasia, flabby ridges, and oral carcinomas. Denture stomatitis is the most common condition which affects the palatal mucosa in about 50% of wearers of complete or partial removable dentures. Most of the lesions are caused by chronic infection (Candida albicans) or mechanical injury whereas allergic reactions to the denture base materials are uncommon. Angular cheilitis (lesions of the angles of the mouth) is characterized by maceration, erythema and crust formation. The prevalence is about 15% among wearers of complete dentures. The lesions have an infectious origin but several local, including prosthetic, or systemic predisposing conditions are usually present. Traumatic ulcers caused by dentures with overextended or unbalanced occlusion are seen in about 5% of denture wearers. Denture irritation hyperplasia, which is caused by chronic injury of the tissue in contact with the denture border, is present in about 12% of denture wearers. Flabby ridge, which is replacement of alveolar bone by fibrous tissue, is present in 10–20%. Finally, there is evidence that chronic injury of the oral mucosa by dentures in rare instances may predispose to development of carcinomas. Most types of lesions are benign and quite symptomless. However, diagnosis may be difficult and the more severe and dramatic tissue reactions to dentures may indicate underlying systemic diseases. In order to prevent or minimize the extent of the lesions, denture wearers should be recalled regularly for an examination of the oral cavity and the dentures. It is important that the examination is carried out by a person who has adequate medical knowledg

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1981.tb01251.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Malignant cells usually have an abnormal DNA content demonstrable by cytophotometry of Feulgen stained tissue. The diagnostic reliability of the technique is reduced because some malignant cells have a normal Feulgen DNA content. If Feulgen DNA content can be combined with measurements of additional cytological characteristics known to vary in malignancy, reliable diagnostic criteria may be forthcoming. In this study, Feulgen DNA content and nuclear area were estimated in 50 squames from the buccal mucosa in each of 14 young adults. Nuclear Feulgen DNA content was determined using an M85 microdensitometer and nuclear area was measured using a Reichert MOP image analyser.In each specimen, Feulgen DNA content was consistent with a nonreplicating cell population. Although nuclear area varied in each specimen, the variation in mean nuclear area among the sample of 14 was not statistically significant. It is concluded that nuclear area provides an accurate baseline against which future measurements on abnormal tissue can be compared.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1981.tb01252.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

AbstractThe capacity of phenol/water extracted lipopolysaccharides (LPS) fromBacteroides, FusobacteriumandVeillonellato induce histamine release from rat peritoneal mast cells has been evaluated by means of a bioassay using atropinized guinea pig ileum and a fluorescence assay. Histamine release was found to be completely complement dependent. It was also found that LPS ofVeillonellahave the greatest capacity to induce histamine release andBacterioideshave the weakest.

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1981.tb01253.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

AbstractThe investigation was undertaken to determine the response to Nobetec®, a modified zinc oxide‐eugenol cement, widely used as a negative control material in pulpal studies, under conditions of high‐ and low‐speed cavity preparation, with and without a cavity liner Dycal®. The pulpal responses were evaluated at intervals of 2 days, 2 weeks and 8 weeks in the permanent maxillary and mandibular incisors in 26 vervet monkeys using labial Class V cavities prepared in 208 teeth. Nobetec® was found to be more irritant to the dental pulp than Dycal® although this difference was not statistically significant and the degree of irritation was low. The pulpal irritation caused by high‐ and low‐speed cavity preparation was similar and choice of speed should be a matter of person

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1981.tb01254.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

AbstractFour dental cements and one bis‐GMA composite were tested in cultures of human periodontal ligament fibroblasts and mouse 3T3 fibroblasts. It was found that these cell types reacted to the cements with different intensities, and that there were differences in evaluation by phase contrast microscopy and succinic dehydrogenase histochemistr

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1981.tb01255.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

AbstractA system in which oral tissues of inbred F344 adult rats and Syrian golden hamster embryos were used in combination with autoradiography was developed for measurement of unscheduled DNA synthesis (UDS). For this, oral mucosa, submandibular gland, tooth germ and mandible in short‐term organ cultures were treated with 4‐nitroquinoline 1‐oxide or N‐methyl‐N‐nitrosourea plus (methyl‐3H)thymidine. Significant numbers of silver grains, indicating UDS, were detected over the nuclei of cells of all these tissues except rat salivary gland after treatment with carcinogens. This autoradiographic method is suitable for detection of UDS in oral tissues in conditions mimicking thosein vivo.Results obtained in this study indicated a potential use of this system for studies on the mechanism of carcinogenesis at a cellular level comparable toin vivocarcinogenesis studies on

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1981.tb01256.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Books reviewed in this article:The Biology Basis of Dental Caries, An Oral Biology Textbook, eds. L. Menaker, R. E. Morhart&J. M. NaviaCollagenase in Normal and Pathological Connective Tissues, eds. D. E. Woolley&J. M. EvansonIntroduction to Analytical Electron Microscopy, eds. Hren, J. I.&Joy, D. C.Clinical Immunology, Vols. I and II, ed. Parker, C. W.Ultrastructural Pathology

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1981.tb01257.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1981.tb01258.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY