ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1975.tb01858.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Abstract.The fine structural characteristics of five adenoid cystic carcinomas of human minor salivary glands and a quantitative assessment of the relative volumes occupied by morphologically defined cell types in these tumors are reported. We observed that the cyst‐like spaces which give the characteristic cribriform pattern to the adenoid cystic carcinoma contain replicated basement membrane‐like material. Material comprising aggregates of fine tubules having a median diameter of 270 A, and rounded, electron dense bodies were noted within duct‐like lumena of one tumor. In addition, dilatation of the intercellular spaces and squamous metaplasia were noted. From 500 electronmicrographs obtained by standardized techniques and used for the morphological part of the study, 175 were selected by a random sampling method and analyzed by the stereological technique of point counting. This method demonstrated that duct type cells occupied 75 % by volume of the tumor in these glands; myoepithelial cells occupied 3 %, acinar cells occupied 2 %, and other tissues occupied 22 % of the tumors. These proportions differ significantly (P<0.001) from our previously published figures for normal specimens of these g

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1975.tb01859.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Abstract:Frozen sections of eight odontogenic cysts, including one keratocyst, were incubated to show the following enzyme activities: NADH2diaphorase, NADPH2diaphorase, glucose‐6‐phosphate dehydrogenase, acid phosphatase and leucinc aminopeptidase. The distribution of lipid was shown by the oil red 0 method. The activities of all three oxidative enzymes were strongest in epithelial cells bordering hyalin bodies and in basal cells in the epithelial lining. Hydrolytic enzyme activity was absent from all but the most superficial epithelial cells but was present in macrophages and, in lesser amounts, in granular material in the same sections. The granular material frequently contained lipid. The lack of hydrolytic enzyme activity in bordering epithelial cells is inconsistent with the theory that hyalin bodies form from degenerating blood vessels. High aerobic oxidative enzyme activity in the same cells also conflicts with the concept that the bodies are a keratinous product. The findings lend support to the theory that hyalin bodies are an epithelial secret

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1975.tb01860.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1975.tb01861.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0904-2512    

DOI:10.1111/j.1600-0714.1975.tb01862.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY