ISSN:0008-6568    

DOI:10.1159/000261319

出版商:S. Karger AG    

年代:1990

数据来源: Karger

ISSN:0008-6568    

DOI:10.1159/000261320

出版商:S. Karger AG    

年代:1990

数据来源: Karger

ISSN:0008-6568    

DOI:10.1159/000261233

出版商:S. Karger AG    

年代:1990

数据来源: Karger

ISSN:0008-6568    

DOI:10.1159/000261234

出版商:S. Karger AG    

年代:1990

数据来源: Karger

ISSN:0008-6568    

DOI:10.1159/000261235

出版商:S. Karger AG    

年代:1990

数据来源: Karger

摘要:

The effect of supplementing the diet or drinking water with lactate dehydrogenase (LDH) on the formation of caries lesions in rats was investigated. Addition of LDH [20 and 5 mg/kg in the high-sucrose (65%) diet, 2 and 1 U/ml in the drinking water (LDH-specific activity 735 U/mg solid)] resulted in significant reductions (p < 0.01) in the number and severity of caries lesions when the enzyme was administered to rats for 4 or 7 days, although no significant differences were found after 14 or 21 days. No differences were observed between effects of addition to water or diet. Fissure caries failed to develop when rats were fed a low sucrose diet (5%) containing LDH (20 mg/kg diet), whereas 50% of the animals in the control group developed lesions. The findings indicate that LDH may play an important role in delaying the onset of caries lesion formation in rats, and that the protection observed may be inversely related to the intensity of the cariogenic challenge.

ISSN:0008-6568    

DOI:10.1159/000261236

出版商:S. Karger AG    

年代:1990

数据来源: Karger

ISSN:0008-6568    

DOI:10.1159/000261323

出版商:S. Karger AG    

年代:1990

数据来源: Karger

ISSN:0008-6568    

DOI:10.1159/000261324

出版商:S. Karger AG    

年代:1990

数据来源: Karger

摘要:

Salivary fluoride concentrations were investigated in 12-year-old children living in areas with low (0.1 ppm) or high (1.2 ppm) fluoride concentration in the drinking water. Unstimulated whole saliva was collected from 27 children from the respective areas every 2nd hour for 46 h except during sleep. The mean salivary fluoride concentration was 0.32 ± 0.013 μmol/l (n = 419) in the low-fluoride (LF) area and 0.87 + 0.047 μmol/l (n = 401) in the high-fluoride (HF) area. No significant rhythm could be found for the diurnal variations in the mean or individual salivary fluoride concentrations. However, in the HF area the individual salivary fluoride concentrations fluctuated widely and random

ISSN:0008-6568    

DOI:10.1159/000261237

出版商:S. Karger AG    

年代:1990

数据来源: Karger

摘要:

The plaque formation of isomaltulose, a sucrose isomer, was examined in 15 human volunteers with both diet and oral hygiene under supervision. The subjects were requested to refrain from all oral hygiene procedures for 3 days and were provided between-meal snacks containing 157 g of 4 test sugars (100% isomaltulose, 70% isomaltulose + 30% sucrose, 50% isomaltulose + 50% sucrose, and 100% sucrose). The study was repeated 4 times over 4 weeks. The isomaltulose diet resulted in the lowest plaque index, while sucrose induced a significantly greater deposition. In the absence of sucrose-containing snacks, mutans streptococci in saliva decreased below the baseline level. These results suggest that isomaltulose may be a suitable substitute for sucrose in between meal snacks.

ISSN:0008-6568    

DOI:10.1159/000261238

出版商:S. Karger AG    

年代:1990

数据来源: Karger