摘要:

In craniofacial surgery, alloplastic materials are used for correcting bony defects. Porous polymethylmethacrylate (PMMA) is a biocompatible and nondegradable bone cement. Porous PMMA is formed by the classic bone cement formulation of methylmethacrylate liquid and PMMA powder in which an aqueous biodegradable carboxymethylcellulose gel is dispersed to create pores in the cement when cured. Pores give bone the opportunity to grow in, resulting in a better fixation of the prostheses. We evaluated the long-term results (n = 14), up to 20 years, of augmentations and defect fillings in the craniofacial area, with special interest in possible side effects and bone ingrowth. The evaluation consisted of a questionnaire, a physical examination, and a computed tomography (CT) scan. There were no side effects that could be ascribed to the porous PMMA. Twelve CT scans showed bone ingrowth into the prostheses, proving the validity behind the concept of porous PMMA.

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID

摘要:

Brown tumor is an important sign of a number of metabolic bone diseases. Normocalcemic hyperparathyroidism, a rare childhood pathologic finding, reveals itself with brown tumors as the only initial sign. In this study, two cases of normocalcemic hyperparathyroidism accompanied by mandibular brown tumors are presented.

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID

摘要:

We report a case of malignant fibrous histiocytoma with intracranial invasion occurring 20 years after radiation therapy for astrocytoma. Magnetic resonance imaging suggested that a dumbbell-shaped tumor arising from soft tissue was pressing the brain. Histopathological findings revealed a storiform pattern with spindle cells such as fibroblasts, histiocytes, epithelioid cells with irregularly shaped nuclei, and bizarre giant cells. Three operations involving craniectomy were necessary because of recurrence.

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID

摘要:

A retrospective study on facial fractures was carried out in the Department of Oral and Maxillofacial Surgery at Tawam Hospital (Al Ain, United Arab Emirates) between January 1, 1998 and December 31, 2001. The study included 144 patients with a mean age of 26.5 years; the most frequently injured patients belonged to the 16- to 20-year-old age group. The male predilection was 83%. Road traffic accident was the most common causative factor (59%), followed by falls (21.5%), accidents where camels were involved (5.5%), work- and sport-related accidents (4.8% and 4.8%, respectively), and assault (4.1%). A total of 53.4% of the patients suffered isolated mandibular fractures, 32.6% had isolated midface fractures, and 13.8% had combined midface and mandibular fractures. Associated injuries were noted in 22.2% of the patients. The number of patients treated increased from 28.3 (1990–1995) to 36 (1998–2001) on an annual average; a reduction in isolated nasal fractures and associated injuries, including facial lacerations, was noted with no change in age or etiology predilection. Sufficient data could not be obtained to determine if the favorable results with the associated injuries were a result of the effect of a compulsory seat belt law introduced on June 1, 1998, but the increasing number of maxillofacial injuries suggests that the seat belt law is ignored in this country.

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID

摘要:

The biophysical characteristics of a new formulation of hydroxyapatite (HA) for craniofacial applications having a rapid set time was evaluated in animals. Using a mature rabbit model, the material was applied in both cranial defects and as a geometrically shaped cranial onlay. Visual and histological assessment was done after 1 year of implantation. The material remained morphologically stable after 1 year, with complete preservation of its onlay shape and stable fill of the cranial defects. A significant osteoconductive response was seen with bone growth across the inner and outer surfaces of the inlays and along the sides of the onlays. No fibrovascular ingrowth or bony replacement of the material itself was evident as a result of the age of the study animals or the compact density of the material. This rapid-setting HA formulation offers similar favorable tissue responses as those of other longer setting HA materials.

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID

摘要:

We report on the feasibility of applying bioabsorbable tacks using a new tack-shooter to fix bioabsorbable plates applied endocranially for the correction of three cases of trigonocephaly. Tacks do not require tapping or tightening because they are applied using a tack-shooter directly into drill holes in the bone. Hence, the technique saves valuable operative time. A 1.5- to 2.0-cm broad supraorbital bar (bandeau) was raised and reshaped. The corrected shape was maintained using a Biosorb plate (Bionx Implants Ltd, Tampere, Finland), and tacks were applied on the endocranial side of the bar. The plate extended a few centimeters laterally beyond the edge of the supraorbital bar, and it was fixed with Biosorb miniscrews and/or tacks affixed to the temporal bones. Other molded bone pieces were fixed using Biosorb plates, screws, and/or tacks. The technique of using tacks was easy, and it provided secure osteofixation. Cosmetic results were excellent, and no complications were encountered except for palpability of plate edges on the right side of the skull in one case.

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID

摘要:

Crouzon and Apert syndromes have been reported to be associated with mutations inFibroblast Growth Factor Receptor 2 (FGFR2)gene in various ethnic groups, but never in Southeast Asian subjects. Therefore, the authors conducted a study to characterize 11 Thai patients: four with Crouzon syndrome and seven with Apert syndrome. All cases are sporadic. Mean paternal and maternal ages were 38.7 and 28.6 years, respectively. Molecularly, all patients were found to have mutations in theFGFR2gene. Three mutations (C278F, S347C, S351C) were detected in all Crouzon patients with two having S351C. The seven patients with Apert syndrome have either S252W or P253R mutation. The authors' findings that sporadic cases were associated with advanced paternal age and that they all had mutations inFGFR2are consistent with previous reports. This is another observation supporting the causative role ofFGFR2mutations in Crouzon and Apert syndromes.

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID

ISSN:1049-2275    

出版商:OVID    

年代:2003

数据来源: OVID