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| 1. |
Hb ananosa orα2111(G18)Ala→Valβ(α2 Mutation) and Hb mulhacen orα2123(H6)Ala→Serβ2(αl Mutation) are two silent stable variants detected by sequencing of amplified dna |
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Hemoglobin,
Volume 19,
Issue 1-2,
1995,
Page 1-6
KazanetzE. G.,
LeonovaJ. Ye.,
WilsonJ. B.,
McMillanS. K.,
WalbrechtM.,
de Pablos GallegoJ. Mi.,
HuismanT. H. J.,
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摘要:
We have identified silent amino acid substitutions in two a chain variants present in families from Iowa, USA, and Granada, Spain. Both involve an alanine residue in the core peptide, namely Ala→Val at position 111 (codon change in theα2 gene; GCC→GTC; Hb Anamosa) and Ala→Ser at position 123 (codon change in theαl gene; GCCOTCC; Hb Mulhacen). The two variants are stable. Sequencing of the amplifiedα2- and al-globin genes greatly facilitated the characterization of the two variants.
ISSN:0363-0269
DOI:10.3109/03630269509069724
出版商:Taylor&Francis
年代:1995
数据来源: Taylor
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| 2. |
Diaminofluorene is more sensitive than benzidine for detecting hemoglobin in erythropoietin responsive J2e cells |
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Hemoglobin,
Volume 19,
Issue 1-2,
1995,
Page 7-19
CallusB. A.,
BusfieldS. J.,
KlinkenS. P.,
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摘要:
We have used the diaminofluorene stain to detect hemoglobin production in J2E cells following erythropoietin-induced differentiation. The pseudo-peroxidase activity of hemoglobin produces a colored product, fluorene blue, which can be measured spectrophotometrically. We found that the absor-bance varied with time and concentration of hemoglobin, making it unsuitable for rapid, routine use. However, hemoglobin content could be determined from the initial reaction rate and this correlated extremely well with the number of benzidine positive cells. When used as a direct cytochemical stain diaminofluorene was shown to be more sensitive than benzidine in detecting hemoglobin-producing J2E cells.
ISSN:0363-0269
DOI:10.3109/03630269509069725
出版商:Taylor&Francis
年代:1995
数据来源: Taylor
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| 3. |
Hb yaizu [β79(EF3)Asp→Asn]: A newβchain variant found in a japanese female |
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Hemoglobin,
Volume 19,
Issue 1-2,
1995,
Page 21-25
HaranoT.,
HaranoK.,
KatsukiT.,
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PDF (251KB)
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ISSN:0363-0269
DOI:10.3109/03630269509069726
出版商:Taylor&Francis
年代:1995
数据来源: Taylor
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| 4. |
Compound heterozygosity for twoβchain variants Hb S [β6(A3)Glu→val] and the high affinity variant Hb san diego [β109(G11)Val→met] |
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Hemoglobin,
Volume 19,
Issue 1-2,
1995,
Page 27-32
WilliamsonD.,
PerryD. J.,
BrownK.,
LangdownJ. V.,
de SilvaC.,
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PDF (307KB)
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ISSN:0363-0269
DOI:10.3109/03630269509069727
出版商:Taylor&Francis
年代:1995
数据来源: Taylor
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| 5. |
Ethics and human genetics, proceedings of the second symposium of the council of europe on bioethics |
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Hemoglobin,
Volume 19,
Issue 1-2,
1995,
Page 33-35
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PDF (164KB)
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ISSN:0363-0269
DOI:10.3109/03630269509069728
出版商:Taylor&Francis
年代:1995
数据来源: Taylor
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| 6. |
Variant list |
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Hemoglobin,
Volume 19,
Issue 1-2,
1995,
Page 37-37
CarverM. F. H.,
KutlarA.,
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PDF (44KB)
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ISSN:0363-0269
DOI:10.3109/03630269509069729
出版商:Taylor&Francis
年代:1995
数据来源: Taylor
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| 7. |
International hemoglobin information center |
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Hemoglobin,
Volume 19,
Issue 1-2,
1995,
Page 39-124
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PDF (4149KB)
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ISSN:0363-0269
DOI:10.3109/03630269509069730
出版商:Taylor&Francis
年代:1995
数据来源: Taylor
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| 8. |
Alphabetical hemoglobin variant list |
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Hemoglobin,
Volume 19,
Issue 1-2,
1995,
Page 125-149
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PDF (821KB)
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ISSN:0363-0269
DOI:10.3109/03630269509069731
出版商:Taylor&Francis
年代:1995
数据来源: Taylor
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