摘要:

Using the flow-cytofluorometric technique, 47 consecutive cases of pituitary tumours were analyzed regarding DNA ploidy and the percentage of cells in different phases of the cell cycle. About 20,000–30,000 cells from each tumour were analyzed. Tumours causing acromegaly showed a higher incidence of high percentages of S-phase cells (≧ 10%) than any other endocrinological type of pituitary tumour. 3 of 6 tumours with high percentages of S-phase cells showed clinically aggressive growth patte

ISSN:0301-1569    

DOI:10.1159/000275641

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

The deleterious effects of decongestant drops on the respiratory nasal mucosa of guinea pigs were studied histopathologically and histochemically. The histopathological changes included: initial goblet cell hyperplasia, squamous metaplasia, increased vascularity, oedema of the corium, mononuclear cellular infiltration and glandular hyperplasia. The histochemical changes indicated: increased secretory activity, increased phagocytic activity as well as disturbance of the vasomotor response.

ISSN:0301-1569    

DOI:10.1159/000275642

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

To investigate the generation mechanism of the –EP in anoxic cochlea, the perilymphatic space was perfused with solution of various K+ concentrations in 38 guinea pigs when the –EP was maximally reduced by anoxia. Although the perfusion of scala tympani and vestibuli with Ringer-Locke solution or that of scala vestibuli with 154 mM K+ solution did not have any effect upon the –EP, the potential was elevated to 0 mV when the scala tympani was perfused with 154 mM K+ solution. Furthermore, the elevation of the potential was less remarkable when the K+ concentration in perfusate was reduced. The level of the potential during perfusion was closely related to K+ concentration in perfusates. The present results strongly suggest that the –EP is the result of the K+ diffusion potential and this diffusion mechanism is performed through the organ o

ISSN:0301-1569    

DOI:10.1159/000275643

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

This report is a presentation of an approach to the prediction of cerebellar-pontine (C-P) angle tumors and four peripheral vestibular diseases from a mathematical statistical point of view. The present study was performed in an attempt to quantify multidimensional, quantitative data. The data analyzed were from a total of 143 patients with C-P angle tumors, Menière’s disease, sudden deafness, vestibular neuronitis, and benign paroxysmal positional vertigo (BPPV). Tests were carried out mainly on otoneurological parameters. By means of discriminant analysis as employed in the quantification method, the patients were classified in the 4-dimensional spa

ISSN:0301-1569    

DOI:10.1159/000275644

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

28 patients with dizziness after head trauma were treated by vestibular neurectomy. Comparisons between the results of surgery and preoperative symptoms and findings showed that the best results were achieved in patients with episodic true vertigo and profound hearing loss. Patients who suffered from constant unsteadiness and/or postural vertigo usually improved, if both audiological and vestibular tests had shown clear pathology. Neurectomy gave poor results if functional tests had shown no pathology or reduced vestibular reaction only. The results support the view that in patients with post-traumatic unsteadiness not associated with hearing impairment, the symptoms probably originate from injury to vestibular pathways central to Scarpa’s ganglion and these patients do not benefit by surger

ISSN:0301-1569    

DOI:10.1159/000275645

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

By performing annual tympanometric screenings of randomly selected children in the winter, the changes in the point prevalence rate of secretory otitis could be estimated during childhood. The tympanometric conditions deteriorated from the age of 4 to the age of 5, and a significant increase in the point prevalence of type B, i.e. flat curve, from 14 to 18% was noted. However, from the age of 5 to the age of 6, an insignificant change was found in the point prevalence of type B (15%) and Eustachian tube dysfunction. In contrast, a marked improvement of the function of the Eustachian tube as well as a drastic fall in the prevalence of secretory otitis to 7 % could be demonstrated from the age of 6 to the age of 7. At each trial some children have dropped out for various reasons. However, the tympanometric conditions of the dropouts largely followed the general pattern of the children who attended all trials.

ISSN:0301-1569    

DOI:10.1159/000275646

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0301-1569    

DOI:10.1159/000275647

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0301-1569    

DOI:10.1159/000275648

出版商:S. Karger AG    

年代:1983

数据来源: Karger