摘要:

Of the 12 cases of verrucous squamous cell carcinoma of the larynx encountered since 1968 at the Department of Otolaryngology of Padua University (including the Verona Section) and the Department of Pathologic Anatomy of the University of Trieste, three are reported, together with an investigation of the nuclear DNA content of the tumour cells. It is suggested that such a study may assist with early detection of verrucous carcinoma. The laryngeal localization of the neoplasm has been evidenced only in some centres. The difficulties in establishing a correct diagnosis for this variant of squamous cell carcinoma are emphasized and the pathomorphological features, as well as the microscopic and macroscopic appearances, are discussed. The prognosis is excellent and the therapy of choice must be only surgical, as radiation has not only proven ineffective, but in some cases has induced anaplasia, leading to a rapid dissemination of the tumour.

ISSN:0301-1569    

DOI:10.1159/000275260

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

The fine structure of human nasal blood vessels was studied in 15 chronic allergic patients. The venules showed gaping of the interendothelial junctions and lamination of the basal lamina. The capillaries displayed numerous endothelial cytoplasmic processes. The arteriolar walls showed thinning and destructive changes. A reciprocal relation between the vascular endothelium and its basal lamina was deduced.

ISSN:0301-1569    

DOI:10.1159/000275261

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

The fine structure of human nasal sero-mucinous glands was studied in 15 chronic allergic patient. There was total absence of the mucous glands, and proliferation of serous elements, with hugely dilated lumina containing large numbers of intact zymogen granules, and absence of microvilli. The relation between the goblet cells and the nasal glands was discussed. An interchange between the serous and mucous elements was deduced.

ISSN:0301-1569    

DOI:10.1159/000275262

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

The localization of T and B lymphocytes in frozen sections of human tonsils was determined using E and EAC binding techniques. It was revealed that there were thymus-dependent areas with E binding lymphocytes in peri- and interfollicular zones. EAC binding lymphocytes were found mainly in the follicles. This suggests that B cells are produced in germinal centres. The present experiment confirmed that human tonsils contain two different kinds of lymphocytes demonstrating selective localizations in the tissues as similar to the lymph nodes.

ISSN:0301-1569    

DOI:10.1159/000275263

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

The temporal bone histopathology of a 2-month-old male with a bilateral cleft palate, cleft lip and polydactylia due to trisomy 13 mosaicism was studied. Anomalies in the ear involved a partial absence of the superior semicircular canal, an abnormally wide lateral semicircular canal, underdeveloped cochlear coils, an abnormally broad modiolus, an undeveloped organ of Corti and an underdeveloped basilar membrane in the basal turn of the cochlea, an unusually wide cochlear aqueduct, and deformed stapedial crura.

ISSN:0301-1569    

DOI:10.1159/000275264

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0301-1569    

DOI:10.1159/000275265

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0301-1569    

DOI:10.1159/000275266

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0301-1569    

DOI:10.1159/000275267

出版商:S. Karger AG    

年代:1976

数据来源: Karger