摘要:

The morphologic development of the vestibular ganglia with their peripheral neuronal connections was followed from terminal mitosis until the adult stage (CBA/CBA mouse). Schwann cells enclose vestibular ganglion cells and their peripheral nerve fibres already on the 15th–16th gestational days. The morphological basis for at least some physiological activity is present already before birth. As compared with the spiral ganglion, the vestibular ganglion and its peripheral pathways become mature as much as 5–7 days earlier. An adult morphology is reached during the first postnatal w

ISSN:0301-1569    

DOI:10.1159/000275746

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

Symptoms in Ménière’s disease are explained by hydrops of the endolymphatic system with recurrent ruptures of the membranous labyrinth. The primary cause of the increased endolymphatic volume appears to be an imbalance between secretion and resorption of endolymph which may be due to an obstruction of the endolymphatic duct and sac, located in the vestibular aqueduct (VA). Non-visualization or narrowing of the latter have been demonstrated by conventional tomography. Also, sclerosis and hypoplasia of the retrolabyrinthine portions of the temporal bone have been documented. By high resolution computed tomography (CT) we prospectively tried to demonstrate morphological alterations in 10 patients with Ménière’s disease. These were compared with a group of 14 non-Ménière patients. Visualization of the VA as well as perilabyrinthine pneumatization were assessed and the width of the retrolabyrinthine part of the temporal bone was measured. Whereas there was a slight difference in the average retrolabyrinthine width (3.8 mm in Ménière versus 5.8 in non-Ménière cases) and degree of pneumatization, there was a distinctly decreased visualization of the VA in the Ménière group. As findings were always bilateral and only 3 of 20 temporal bones showed peripheral hypopneumatization, possibly due to chronic otitis mediathe theory of a predisposing constitutional abnormality must be taken into consideration. However, we were not able to confirm a statistically proven usefulness of the CT technique in identifying an anatomical abnormality which is directly in correlation with the side of the lesion in cases of unilateral M

ISSN:0301-1569    

DOI:10.1159/000275747

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

12 cases of unilateral labyrinthectomy, 3 cases of VIIIth nerve section, 22 cases of streptomycin sulfate infusion into the middle ear cavity and 8 cases of bilateral vestibular a-functions underwent vestibular training. Our training is very useful for regaining equilibrium and for evaluating the effects of training on equilibrium by recording the gravity center movements.

ISSN:0301-1569    

DOI:10.1159/000275748

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The ototoxicity and nephrotoxicity of netilmicin were compared with those of dibekacin, kanamycin and amikacin using rabbits. Groups of 5 rabbits each were given doses of 50 or 100 mg/kg of either one of the four drugs for 30 days, and 10 days after the last injection, all animals were prepared for histopathological studies. Results show the least ototoxicity of netilmicin in comparison to the other three antibiotics. It has been concluded that the low ototoxicity of netilmicin is due not to its lack of accumulation in the perilymph but to its low toxicity to the hair cells.

ISSN:0301-1569    

DOI:10.1159/000275749

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The purpose of this study is to investigate the diagnostic value of using brain stem auditory evoked potentials (BSEP) in patients with the lateral medullary (Wallenberg’s) syndrome. The observed changes included: prolongation of the interpeak latency intervals from wave I to V and III to V; prolongation of the interaural latency difference for wave V; splitting or absence of wave III, and the presence of a broad partly fused wave III-V complex. The present study showed that BSEP can be used to confirm the diagnosis of this syndrome and ascertain the site of the lesio

ISSN:0301-1569    

DOI:10.1159/000275750

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The effect of atropine on the eustachian tube function was studied by means of a recently designed method. The results out of 20 examined ears showed that atropine significantly reduced both active and passive functions of the eustachian tube. The findings are discussed and it is concluded that the method used might be a valuable tool in forthcoming studies of pharmacological effects on the eustachian tube function.

ISSN:0301-1569    

DOI:10.1159/000275751

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

50 patients with advanced malignancy treated with bleomycin were assessed for taste abnormality. 5 (10%) cases were found to have some degree of taste impairment. Gustation sense returned to normal within 10–12 weeks following discontinuation of bleomycin therapy. The possible pathophysiology of gustotoxicity is discussed in the light of the available literatur

ISSN:0301-1569    

DOI:10.1159/000275752

出版商:S. Karger AG    

年代:1985

数据来源: Karger

ISSN:0301-1569    

DOI:10.1159/000275753

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The clinical and pathological findings in 4 cases of primary giant cell carcinoma of the larynx are reported. This variant of large cell carcinoma resembles the well-defined giant cell carcinoma of the lung. It has to be distinguished from other types of carcinoma of the larynx. This can be difficult on small biopsy specimens and the definite diagnosis may only be established after the detailed examination of the excised tumour. The highly malignant behavior of the laryngeal type was noted. To our knowledge this is only the second report on giant cell carcinoma of the larynx.

ISSN:0301-1569    

DOI:10.1159/000275754

出版商:S. Karger AG    

年代:1985

数据来源: Karger