摘要:

Screening tympanometries were performed at 2-week intervals in 373 children (mean age 4¼ years) cared for in 10 day-care centers in order to evaluate the incidence of secretory otitis media (SOM). The incidence was found to depend on the age of the children and the maximum level was at the age of 1 (0.36/child/month); the mean incidence was 0.16/child/month. The highest incidence and the largest number of children with prolonged SOM were both found in the 1-year-olds. The overall morbidity of SOM in the 373 children was 56%

ISSN:0301-1569    

DOI:10.1159/000275715

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

No activity of the plasmin and plasminogen activators could be detected in middle ear effusion (MEE). A streptokinase proactivator, which was not plasminogen and markedly enhanced the activation of plasminogen by streptokinase, could be detected. MEE had an apparent inhibitory activity against both thiol protease (papain) and serine proteases (plasmin and trypsin). All these findings indicate that MEE contains unsaturated protease inhibitors and is in a state of predominance of inhibitors over fibrinolytic activity.

ISSN:0301-1569    

DOI:10.1159/000275716

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Qualitative and quantitative analyses of sterol derivatives in the tissue of cholesteatoma and cholesterol granuloma were performed by gas-liquid chromatography, mass spectrometry and mass fragmentography after the extraction of total lipids with organic solvents. Cholesterol was the major component in both tissues. The molar ratios of cholesterol to lipid-bound phosphorus in cholesterol granulomas were higher than those in cholesteatomas. In addition, Δ7-cholestenol (lathosterol) was contained in all tissues of cholesteatoma examined. However, cholesterol granuloma tested did not contain Δ7-cholestenol, indicating that the metabolism of cholesterol differed from that in cholesterol granulom

ISSN:0301-1569    

DOI:10.1159/000275717

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

17 biopsies of denervated facial muscles, the zygomatic, the orbicularis oris and the levator labii muscles, showed atrophic myofibers in most cases. There was loss of fiber typability when applying the NADH, the MAG and the alkaline ATPase reactions. The acid ATPase preparations allowed differentiation of myofibers into type I and type II without subtypes. Contrary to normal facial muscles that are richly endowed with motor endplates, no neuromuscular junctions were observed in denervated muscle fibers except one example which might have been obtained by false sampling from the marginal area of denervation or might be the result of partial reinnervation due to sprouting axons from the neighborhood. There was no correlation between the degree of muscle fiber atrophy and the duration of the paralysis. However, fibrosis corresponded to length of denervation. The presence of highly atrophic muscle fibers even 36 years after denervation indicates that the final aim of facial nerve surgery, namely the reinnervation of denervated facial musculature may still be achievable. However, endomysial and perimysial fibrosis may have a considerable impact on the final outcome of such facial nerve surgery. Unsatisfactory correlation between morphological and clinical as well as electromyographical findings in denervated facial muscles requires individual morphological study of each biopsy to assess the probable outcome of reconstructive facial nerve surgery. It therefore appears reasonable even in long-standing facial paralysis, to biopsy denervated facial muscles before or during surgical reanastomosation of the facial nerve. This study provides hints that morphological examination of denervated facial muscles may supplement clinical, electrophysiological, and possibly biochemical diagnostic findings.

ISSN:0301-1569    

DOI:10.1159/000275718

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

The attitude of phosphohexoseisomerase (PHI), a glycolytic enzyme, in parotid and submandibular saliva of healthy human control subjects of different sex and age was studied flow rate dependent. The results obtained from this group were compared to the PHI activity measured in the saliva of patients suffering from salivary gland diseases. Significantly elevated salivary PHI levels were found in chronic sialadenitis, while in sialadenosis, parotid gland infarction and parotid cysts the enzyme activity was within the normal range. Single patients suffering from parotid gland tumors showed elevated PHI values. A possible role of salivary PHI activity for the differential diagnosis of salivary gland diseases is discussed.

ISSN:0301-1569    

DOI:10.1159/000275719

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

The Eustachian tube function requested from flying personnel today is generally regarded as acceptable if hearing and otoscopic findings are normal and there is no history of ear disease. Since increasing performance of modern aircrafts place more rigorous demands on the equilibrating capacity of the Eustachian tube and difficulty to clear the ears already is the most common cause of temporary grounding among flying personnel, the present requirements for tubal function might gradually get more and more inefficient. Inability to equilibrate in flight may lead to temporarily reduced hearing, acute ear pain and alternobaric vertigo that will affect the pilot’s capacity and thus constitute a problem of flight safety. A testing procedure that makes it possible to continuously measure the middle ear pressure in subjects with intact eardrums during simulated flights in a pressure chamber would introduce a possibility to find basic medical standards of Eustachian tube function to be used in the selection of flying personnel. Student pilots, accepted for primary flight training, were examined in the present study by such a method. A comparison is made with the results of other tests of the Eustachian tube function in order to find out the relevance of the latter tests in the selection of flying personnel. The results are presented and discusse

ISSN:0301-1569    

DOI:10.1159/000275720

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

A coherent and stable method was implemented for constructing the cumulative slow-phase eye position of the post-caloric nystagmus. Similarity and variability analyses performed on the derived responses (inter- and intrasubject) of 6 normals confirmed the homogeneity of the measure. A pilot study on one pathological case showed marked deviation from the normal responses.

ISSN:0301-1569    

DOI:10.1159/000275721

出版商:S. Karger AG    

年代:1984

数据来源: Karger

ISSN:0301-1569    

DOI:10.1159/000275722

出版商:S. Karger AG    

年代:1984

数据来源: Karger

ISSN:0301-1569    

DOI:10.1159/000275723

出版商:S. Karger AG    

年代:1984

数据来源: Karger