摘要:

ABSTRACT.A total number of 112 children with congenital hypothyroidism were diagnosed in all Children's Hospitals and Pediatric Wards in Sweden during the 7‐year period 1969–1975. Since it may be assumed that all cases of congenital hypothyroidism, which were diagnosed during that period were seen in one of these hospitals, the incidence of congenital hypothyroidism in Sweden can be calculated to be 1:6900 live births. In spite of an efficient National Health Care Program for Infants the diagnosis was delayed until after an age of three months in 52% of the cases. This fact supports the view that mass screening of newborns for congenital hypothyroidism has to be introduced in Sweden. However, the beneficial effects of such a program cannot be fully elucidated until it has been considered whether earlier instituted treatment would have improved the outcome of children in whom a diagnosis was made after 3 months of

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb16268.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryOf 178 normal breastfed infants enrolled during the first 9 days of life, 129 (59 males and 70 females) completed the planned period of observation to 112 days of age. Limited amounts of formula and beikost were permitted and intakes of these foods were determined. Length and weight were measured at standardized ages and blood for serum chemical determinations was obtained.Data from this study were combined with similar data published (1) previously. Thus, data are now available concerning 117 males and 116 females. Means, standard deviations and percentile values, including 5th and 95th percentile values, for length and weight at. tained and for rates of gain in length and weight between various ages are presentedMeans and percentile values for intake of calo. ries from formula and beikost and for serum chemical values are presented. In instances where analysis of variance indicated statis. tically significant effects of age and/or sex serum chemical values have been tabulated or an age‐ and/or sex‐specific ba

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb15135.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

ABSTRACT.The number of new paediatric patients accepted for treatment by regular dialysis and transplantation increased more slowly than in previous years. Survival in children above 10 years appeared to be better with all modes of therapy than in younger children. The only improvement in survival noted among the different treatments was in patient and graft survival of living donor transplants. A quarter of all children transferred to home dialysis were less than 10 years of age. Nephronophthisis and Henoch‐Schönlein nephritis emerged as major primary renal diseases. In 1975 the proportion of retransplants in children rose and living donor grafts from fathers were more common than from mothers. Evening dialysis was practised more frequently in both hospital and home dialysis and rehabilitation in these patients seemed to be better than for those dialysed at other times. Renal osteodystrophy was present in at least half of all children dialysed for more than 1 year. The degree of growth retardation was affected by sex, chronological age and the primary renal disease. Body height on dialysis and after transplantation progressively reduced in the majority of children. Growth seemed to be more impaired in boys than in girls on dialysis. Bone age advanced faster than height age especially in girls. The pubertal growth spurt was usually delayed and depressed on long‐term dialysis and the development of genitalia and pubic hair as well as menarche was reta

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb16269.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb06147.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb06148.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb15136.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

ABSTRACT.The functional and dimensional components of the oxygen transporting system was studied in 17 female and 11 male patients suffering from anorexia nervosa. Both groups were 14.9 years old, on average, and had lost about 25% of their weight. Measurements at rest included blood and heart volume, heart rate, blood pressure, oxygen uptake (Vo2), RQ, blood lactate (LA) and in 6 of the patients cardiac output. During bicycle ergometry the determinations of heart rate, blood pressure, LA,Vo2and cardiac output were repeated and maximal aerobic power was determined. A low metabolic rate with bradycardia and hypotension was apparent at rest. Blood and heart volume was decreased proportionally to the weight loss. On a given work loadVo2was lowered to the same extent as the resting metabolic rate. At maximal effortVo2was reduced out of proportion to the circulatory dimensions and maximal heart rate was low. During exercise cardiac output was normally related toVo2and stroke volume was maintained, indicating a normokinetic circulation and an unimpaired myocardial function. The main cause of the low maximal aerobic power seems to be the reduced muscle mass.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb16270.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb15137.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb15138.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

ABSTRACT.131 patients suffering from meningitis due toHaemophilus influenzaeorparainfluenzaewere re‐examined after 1–15 years, using hospital records, questionnaires, and audiological examination, especially to compare chloramphenicol and ampicillin therapy. Mortality was 3.8%. Subdural effusions occurred in 14.5% of cases uni‐ or bilaterally. There was deafness in 2.3%, and moderate hearing loss in 8.4%. Convulsions appeared later in 6.9%. The final otucome was good in 60%. The most important factors in prognosis seemed to be the severity of the symptoms and the condition of the patient on admission to hospital. No clear difference was seen between the results of chloramphenicol and ampicillin therapy, but total loss of vestibular function was found in 3 cases in the ampicillin group, and in none in the chloramphenicol group. In mortality and deafness, the differences in outcome were similar, although not statistically significant. As these observations show, the therapy used inHaemophilus influenzaemeningitis needs re‐eva

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1978.tb16271.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY