摘要:

ABSTRACTThe diagnosis of Cow's Milk Protein Allergy was considered in 303 infants aged less than 1 year, who presented with one or more of the following symptoms: acute reaction related to cow's milk proteins (CMP) ingestion, severe colics, persisting vomiting, protracted diarrhea with or without blood and mucus, failure to thrive, eczema, respiratory symptoms, such as chronic rhinitis and wheezing. A diagnosis of CMPA was confirmed in 148 cases (60%): 125 relapsed on milk challenge, 23 were not challenged because of acute reactions at onset, presence of specific IgE (RAST and prick), and improvement on milk free diet. Familial atopy, familial history of CMPA and previous acute gastroenteritis were significantly more frequent in cases than in 191 age matched controls. Breast feeding was not more common or of longer duration in controls, compared to cases. Mean IgE serum levels were higher (46.3 U/ml) in cases than in controls (17 U/ml), while specific Cow's Milk Protein IgE were found in 71/148 cases (48%). 15 infants entered the study while on breast milk, because of the confirmed relation between their symptoms and CMP on the maternal diet. These infants had a higher prevalence of IgE mediated problems. All cases improved on a milk free diet but in 26 (17.8%) a further modification of the diet was required after the first prescription. Milk challenge was monitored by simple laboratory tests: all cases who had symptoms on challenge showed at least one test modification. Six infants, with no history of acute reaction, showed severe self‐limited clinical symptoms at challeng

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb10877.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb18157.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb10855.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb10856.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb10866.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb10867.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

ABSTRACT.During the five‐year period, January 1980 to December 1984, 149 babies of extremely low birthweight (ELBVV; 501–1000 g) and 296 of very low birthweight (VLBVV; 1001–1500 g) were admitted to King's College Hospital, Neonatal Intensive Care Unit. The survival rates were 51.7 % and 82.8 % respectively. There were more peri‐ and postnatal problems in the ELBVV babies than the VLBW babies and these differences were highly significant. All surviving babies born between January 1980 and December 1982 were followed up until aged two. The ELBW children had a higher incidence of neuro‐developmental sequelae than those of VLBW especially when both major and minor problems were considered. Their developmental quotients were lower at one and two years. Significantly more ELBW children were of short stature and low weight (<3rd centile). By two years of age the differences between ELBW and VLBW children in stature and mean DQ had

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb10590.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb10794.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb18158.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

ABSTRACT.The general background to child health in Saudi Arabia is reviewed. Information is provided on the social and demographic characteristics of the population, on common health indicators, on the health care system and its utilization, and on the general pattern of childhood morbidity and mortality. The unprecendented socioeconomic development has transformed the health care system. In 15 years the number of nurses have increased from 3261 to 29896, physicians from 1172 to 14335, primary health care centers from 591 to 1821, and hospital beds from 9036 to 30707. In spite of this progress, the disease pattern seems to resemble that of some developing countries with more limited resources. Parasitic diseases are still widespread, and sample surveys have indicated suboptimal nutrition of rural preschool children. Recent estimates on the infant mortality rate have ranged from 65 to 120 per 1000 live births. The preferred marriage partner is a close relative, and genetic diseases, such as hemoglobin disorders, are common in certain areas. Thus, the prevalence of alpha thalassemia is reported at 50 percent, and the sickle cell trait at 4.4–20 percent in sample surveys from the Eastern Province. The modest educational attainment of the mother, the heavy reliance on foreign manpower in all sectors, including the health sector, and the further development of the primary health care system are key issues today. It is emphasized that demographic and epidemiological information from Saudi Arabia is scarce and frequently uncertain, and that further studies are needed to identify the health needs of Saudi childre

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1988.tb10868.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY