摘要:

Abstract.Biering‐Sørensen, F., Jørgensen, T. and Hilden, J. (Municipal Agency of Infant Health Visitors, Copenhagen, and Institute of Human Genetics, University of Copenhagen, Copenhagen, Denmark). Sudden infant death in Copenhagen 1956–71. II. Social factors and morbidity. Acta Paediatr Scand, 68: 1, 1979.—131 cases of the Sudden Infant Death Syndrome (SIDS) among infants born in the Municipality of Copenhagen during 1956‐71 were analysed on the basis of data collected prospectively by the infant health visitors and abstracted from police reports. Compared with controls, a significantly larger number of SIDS infants had been born out of wedlock, were living only with their mother, had parents in a less secure occupation, lived in more crowded, poor‐quality dwellings and districts. The “home standard” was lower among the SIDS families, including a lower standard of infant care, a higher percentage of not keeping the appointments with the infant health visitors, and a lower mental capacity in the mothers; there was no difference with respect to the mother's physical capacity. More congenital malformations and more cases of asphyxia were found among the SIDS infants, and a significantly larger number of the SIDS infants had been admitted to hospital, with a tendency to being kept there longer. It is concluded that a relationship exists between poor social conditions, increased morbidity, and SIDS. At the same time, it is pointed out that during recent years the differences between cases and controls as regards certain of the social parameters studied

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb04422.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb06182.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb06183.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb06174.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Kastrup, K. W., Andersen, H., Eskildsen, P. C., Jacobsen, B. B., Krabbe, S. and Petersen, K. E. (Children's Hospital, Fuglebakken and Herlev Hospital, Copenhagen, Denmark). Combined test of hypothalamic—pituitary function in growth retarded children treated with growth hormone. Acta Paediatr Scand, Suppl 277: 9, 1979.—In 23 growth retarded children two consecutive insulin tolerance tests (ITT) were performed to establish a diagnosis of growth hormone (GH) deficiency. Nine children did not respond (GH peak value less than 8 mU/l), whereas 14 were classified as having partial GH deficiency (GH peak value less than 20 mU/l). All were treated for an average period of 40 months with human growth hormone (HGH). In a combined stimulation test at the end of the treatment period 9 children demonstrated a persistent GH deficiency, whereas a normal response was found in 14 of the previous partial GH deficient children. During treatment the monthly growth rate rose from 0.21 cm to 0.58 cm in the GH deficient children and from 0.31 cm to 0.70 cm in the partial deficient children, in most of whom spontaneous pubertal development occurred during treatment. Somatomedin (SM) values were decreased in the GH deficient children before and after treatment but increased to normal levels during treatment. Growth velocity in these children during treatment was correlated to SM values before treatment. In the partial GH deficient children SM values were subnormal before but normal after treatment. This supports the assumption that in some children with constitutional delay in puberty a reversible functional hypopituitarism exists, which is normalized after the onset of puberty, due to androgens sensitizing growth hormone releasing mechanisms. Treatment with HGH may induce increased growth velocity in some of these patie

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb06184.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb06175.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Biering‐Sørensen, F., Jørgensen, T. and Hilden, J. (Municipal Agency of Infant Health Visitors, Copenhagen, and Institute of Human Genetics, University of Copenhagen, Copenhagen, Denmark). Sudden infant death in Copenhagen 1956–71. III. Perinatal and perimortal factors. Acta Paediatr Scand, 68: 11, 1979.—139 cases of the Sudden Infant Death Syndrome (SIDS) among infants born in the Municipality of Copenhagen during the period 1956–1971 were analysed on the basis of data collected from police reports and (for 131 cases) from the infant health visitors' records. In the SIDS group there was a greater male preponderance than among others dying in the same age range. Compared with the living controls, the SIDS mothers had attended less prenatal examinations, more often delivered their babies at home; the SIDS parents were younger, and yet the SIDS infants were less often firstborns. There was no difference with respect to history of abortions, maternal state of health during pregnancy, or events at delivery. The age at death for the SIDS infants is of a distribution similar to that for fatal respiratory infections. Prematures died later than matures, but this difference is not statistically significant. It is concluded that perinatal factors and SIDS are correlated, but owing to changes in predisposing factors and decreasing differences between cases and controls in recent years as well as interdependence of the factors, it seems doubtful whether the incidence of SIDS can be reduced by alleviating the above‐mentioned unfavoura

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb04423.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb06176.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.P. C. Eskildsen, B. B. Jacobsen, K. W. Kastrup, S. Krabbe, P. E. Lebech and K. E. Petersen (The Children's Hospital Fuglebakken, Herlev Hospital and Frederiksberg Hospital, Copenhagen, Denmark). Combined test of hypothalamic‐pituitary function in growth‐retarded children treated with growth hormone. Acta Paediatr Scand, Suppl. 277: 14, 1979.—A total number of 23 patients treated with human growth hormone were retested by use of a combined pituitary stimulation test. Plasma concentrations of GH, FSH, LH, TSH, T4, T3, prolactin (PRL), ACTH and cortisol were measured before and after stimulation with hypoglycemia, TRH and LHRH. The test was performed in patients with persistent GH deficiency (group A) and patients with transitory GH deficiency (group B). In group A a normal pubertal development was found in three patients, whereas in prepubertal subjects the FSH/LH responses were smaller than those of prepubertal patients in group B. Also plasma ACTH increase was less pronounced in group A patients than in group B. In contrast, the plasma TSH and PRL responses were more sustained in group A than in group B. The secretory pattern of TSH and PRL was comparable in the two groups of patients. Thus, in patients with persistent GH deficiency additional multiple disturbances of the hypothalamic‐pituitary function often appeared whereas in most patients with transitory GH deficiency the combined pituitary test was normal at the reinvest

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb06185.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Sjölin, S. and Smedby, B. (Departments of Paediatrics and Social Medicine, University Hospital, Uppsala, Sweden). The state of health of Swedish children. An attempt is made briefly to describe the present health problems of Swedish children. The report is based on data available in official statistics or collected from special studies. It is concluded that the general state of health of Swedish children is good when assessed by commonly used criteria. The mortality pattern is dominated by perinatal and accidental deaths, but also neoplasms are of importance. There are indications that genetic and handicapping disorders, and psychosocial maladjustment will receive more attention in the future

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1979.tb06156.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY