摘要:

Asthma is a term that has been used for centuries to describe states of breathlessness associated with wheezing. However, there are well‐known difficulties in defining asthma, as it encompasses such a broad clinical spectrum ranging from mild, rapidly reversible, broncho‐spasm to severe, intractable, chronic airflow obstruction. Moreover, reversibility of airflow obstruction, a cardinal feature used to identify asthma, may be demonstrated only with difficulty in certain cases, such as severe, acute asthma attacks, which necessitate several days of treatment before any reversibility can be achieved.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133019.x

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

Immediate, type 1 allergic reactions occur following interaction between allergen, immunoglobulin E (IgE), and the mast cell or basophil. Allergen‐induced activation of these cells leads to the release of a number of mediators that are responsible for the symptoms observed during an allergic reaction. Recent progress in elucidating the structures, and in developing syntheses for platelet aggregating factor and the leukotrienes, promises to increase our understanding of the immunopharmacology of allergic and inflammatory reactions. The need for the standardization of allergen extracts is emphasized, and current activity in this area is highlighted.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133020.x

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

The clinical syndrome of anaphylaxis may be produced by a number of mechanisms. The life‐threatening clinical features are angioneurotic oedema, bronchospasm, cardiovascular collapse and pulmonary oedema. The initial treatment consists of general resuscitation plus adrenaline. In shock, colloid solutions should be used to restore blood volume. The pulmonary oedema that occurs is a membrane oedema, and should be treated with artificial ventilation, positive end expiratory pressure, and volume replacement. After a reaction, all available tests should be used to determine the cause, and the patient should be given a warning letter describing the evidence for attributing his reaction to the determined cause. (This should be done in addition to the provision of any identification bracelet.) Pharmacological pretreatment is a valid preventive manoeuvre, but is not 100% reliable.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133021.x

出版商:Wiley    

年代:1984

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133022.x

出版商:Wiley    

年代:1984

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133024.x

出版商:Wiley    

年代:1984

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133025.x

出版商:Wiley    

年代:1984

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133027.x

出版商:Wiley    

年代:1984

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133028.x

出版商:Wiley    

年代:1984

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133029.x

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

This article gives background information on the taxonomic relationships between plants, for clinicians, patients and students of allergy. A list is provided of plants considered potentially allergenic either by inhalation of pollen or by ingestion of grain products. Distributions in Australia of plant species important in assessing pollen‐related allergy, and the range of foodstuffs that contain cereal‐grain protein, are also indicated. Particular emphasis is placed on the grasses because of their importance as producers of both grain and pollen.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1984.tb133030.x

出版商:Wiley    

年代:1984

数据来源: WILEY