ISSN:1422-6405    

DOI:10.1159/000146476

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Clusters of chief cells from a fragment of human parathyroid adenoma possess relatively few rough endoplasmic reticulum (RER) cisternae with scattered annulate lamella (AL) pores in cytoplasmic sectors close to the nucleus. Some of these cisternae exhibit winding profiles with smooth segments lying very close to the outer nuclear membrane. Other groups of cells exhibit well-developed stacks of RER either in continuity with or separated from AL. Two other tumor fragments show chief cells with few RER cisternae scattered in the cytoplasm and possess stacks with various amounts of AL and/or paired cisternae (PC), occasionally at perinuclear sites. Compartmental continuity between AL and PC is a frequent finding. Pore density in AL varies considerably between the stacks from different cells.

ISSN:1422-6405    

DOI:10.1159/000146477

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Male adult Wistar rats were treated for 8 weeks with an organosilicone [2,2-dimethyl-4-(chloromethyl)-1,3-dioxa-2-silacyclopentane] employing two different dosages (25 and 50 mg/kg body weight i.p. daily) and the changes in the tubular apparatus of the kidney were investigated employing histological and enzyme-histochemical methods. The effects, more pronounced at the higher dosage, were the following: The brush borders of the proximal tubules were stuck together and disintegrated; only few epithelial cells remained intact showing a decreased activity of nonspecific esterases and the increase of β-hydroxybutyric acid dehydrogenase. The nuclei of most of the epithelial cells in the distal tubules were dislocated towards the enlarged lumen and the cytoplasma showed a decrease of nonspecific esterases and an increase of β-hydroxybutyric acid dehydrogenase. The collagen fibers in the walls of the collecting tubules were dislocated and disintegrated with a discontinuous border of Mg2+-ATPase; the nuclei of the epithelial cells were pyknotic, the cytoplasma showed an increase of β-hydroxybutyric acid dehydrogenase. The induced changes were partially reversible after a recovery period of 8 wee

ISSN:1422-6405    

DOI:10.1159/000146478

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

We have studied the karyometric development of the nuclei of the ependymal cells and neurons of the subfornical organ and the area postrema in the male albino mouse from the 5th to the 190th postnatal day. We have found similar patterns of development in both although the area postrema showed more significant postnatal oscillations than those of the subfornical organ, suggesting a more intimate chronological relationship to gonadal development. We have furthermore analyzed the development in two experimental groups: in the one animals were castrated at birth, in the other, castration was made on the 20th postnatal day. We have found that neonatal castration produced a significant decrease of nuclear sizes; this was more evident in the subfornical organ than in the area postrema in earlier stages of development while the response was similar in both at peripuberal ages. The response to prepuberal castration was similar in both organs.

ISSN:1422-6405    

DOI:10.1159/000146479

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

The epithelial height and myometrial and endometrial characteristics of the fundus, corpus and neck regions of the uteri of 28 virgin West African indigenous gilts in four age groups (6–8 10–12 16–18 and 20–22 months) were histometrically evaluated. Though regionally stable, the height of luminal epithelial cells was, respectively, reduced and enhanced in the fundus and neck regions by 10–12 months. The myometrium was thinner in the fundus and was severely reduced in the corpus region in gilts aged 16–18 months. Contrarily, the endometrium was regionally stable in thickness but underwent some thickening in the corpus of 16 to 18-month-old gilts.The respective occurrence of muscular and glandular tissues in the myometrium and endometrium was regionally influenced while older gilts had more circular muscles than the others. Generally, over 70% of the glands and 60% of the muscles were complex glands and longitudinal muscles, respectively. Results depict the nonuniform growth rates of different uterine tissues in the different regions and suggest that the improvement in the litter-carrying capacity of the uterus in these pigs continues well af

ISSN:1422-6405    

DOI:10.1159/000146480

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Necropsies were obtained from 5 muscles from 5 young women.The muscles subjected to morphometrical analysis were the deltoid, brachial biceps, vastus lateralis, gastrocnemius and soleus. Results of measurements taken indicate significant differences in fibre sizes and fibre type composition in analogous muscles between individuals and between different muscles within individuals. Differences.were also encountered in muscle fibre size during rigor mortis for up to 48 h after death. Our results suggest that the fibre size variability between individuals determined from necropsy samples will contain a component of induced variation not found in muscle biopsies.

ISSN:1422-6405    

DOI:10.1159/000146481

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

In a series of 215 anteroposterior X-ray films, a study was made of the horizontal distance between the pedicles of each lumbar vertebra, first of all sequentially, describing the morphology adopted by the lateral limits of the canal, and secondly determining the absolute value for each level separately and in relation to the variables of sex and age. The absolute value of this distance at each level is related to the thickness of the pedicles and the width of the vertebral bodies of L3 and L4. The values obtained were tested with the appropriate statistics in each case.

ISSN:1422-6405    

DOI:10.1159/000146482

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Histological and ultrastructural changes of hypophyseal gonadotropic cells of rats which received a 15% solution of ethyl alcohol for 6 months were studied. Light microscopy revealed hyperplasia and hypertrophy of these cells; some contained a vacuole of varying size. Ultrastructural analysis showed that this vacuole originated from, and anastomosed with, dilated cisternae of the granulated endoplasmic reticulum. Vacuolated cells in the pituitary of alcoholized rats were identical with cells observed after surgical or chemical castration. The development of these alcohol-induced castration cells is achieved in four stages.The first stage was characterized by beginning hydropic degeneration and other still reversible alterations. Cells in the second and third stages seemed already irreversibly on their way to decay.The fourth stage was represented by typical signet-ring cells. Our results offer a morphological basis to the adoption of a biphasic effect of alcohol on gonadotropic secretion.

ISSN:1422-6405    

DOI:10.1159/000146483

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

We examined non-granulated pituitary cells (folliculo-stellate cells and anterior and posterior marginal cells of the pituitary cleft) in lactating and virgin female rats by means of electron microscopy and morphometry. Ultrastructure and morphometric parameters of the cells lining the pituitary cleft were similar in the two groups of animals. On the contrary, folliculo-stellate cells showed a marked nucleocytoplasmic activation in lactating rats in the electron microscope, which was confirmed by morphometric measurements. These results are not consistent with the hypothesis that the three cell types share the same reactivity during pituitary hyperfunction and that they have a common function, as suggested by purely morphological studies in various endocrine conditions. We believe that quantitation of cell response during such stimuli could be useful to further elucidate this matter.

ISSN:1422-6405    

DOI:10.1159/000146484

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

In the present investigation partial degeneration of adrenergic and cholinergic nerves of the heart of guinea pigs following methotrexate treatment has been reported. No appreciable change was observed in the autonomic nerve fibres after 3 days of treatment. However, after prolonged treatment some nerve fibres showed signs of degeneration and a few adrenergic and cholinergic nerve fibres had disappeared.

ISSN:1422-6405    

DOI:10.1159/000146485

出版商:S. Karger AG    

年代:1988

数据来源: Karger