摘要:

In recent years, skin grafting has evolved from the initial autograft and allograft preparations to biosynthetic and tissue-engineered living skin replacements. This review details the pioneering work of numerous investigators that led to the following precursors of tissue-engineered skin replacement: cultured autologous keratinocyte grafts, cultured allogeneic keratinocyte grafts, autologous/allo-geneic composites, acellular collagen matrices, and cellular matrices. It also discusses the rationale for the development of the newer products and describes the technical advances leading to the development of Apligraf®, a tissue-engineered human skin product.

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID

摘要:

The abstract functions as the “road-map” to the study. It describes the purpose of the trial (i.e., the specific treatment the trial will assess) and the methods that were used. It presents the results that are crucial to the conclusions drawn from the trial and gives a brief statement of the researchers' conclusions. The abstract also should point out to readers why the trial was necessary and how the results will be useful to them.

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID

ISSN:1076-2191    

出版商:OVID    

年代:1998

数据来源: OVID