ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

In a double-blind crossover study, 12 depressed inpatients receiving bilateral electroconvulsive therapy (ECT) were given 22.5 mg oxazepam or placebo (identical tablets, randomized order) the night before treatment. Seizure duration was measured using the cuff method and a total of 20 pairs of measurements were made. Mean duration after oxazepam administration was 0.9 s longer than after placebo; this difference was not statistically significant. The relevant lower one-sided 95% confidence limit was −4.1 s. Single administration of oxazepam, 22.5 mg, has little average effect on seizure duration in ECT.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

Treatment with electroconvulsive therapy (ECT) of medically ill geriatric patients with affective disorders is described. Of 135 patients to whom ECT was administered in 6 years, 55% were over 60 years of age. One-third (45) exhibited cardiovascular (62%), central nervous system (15%), or other medical conditions (22%) increasing the risks of the treatment. Treatment strategies are described.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

The relationship between hemodynamic changes induced by electroconvulsive therapy (ECT) and age was studied in 13 patients. Their average age was 43 years (range 20–64 years). Heart rate, arterial blood pressure, and rate-pressure product (RPP) all increased significantly following ECT. There was an inverse relationship between age and the magnitude of the chronotropic response, the percentage increase in diastolic and mean arterial blood pressure, and the RPP. Duration of the electroencephalographic and motor seizures was also inversely related to age.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

The authors review their experience with brain magnetic resonance (MR) imaging in elderly patients with depression referred for electroconvulsive therapy (ECT). A variety of brain changes were identified on the pre-ECT MR scans of these patients, including cortical atrophy, subcortical encephalomalacia, lateral ventricular enlargement, and lesions of the pons. The authors examine the effects of these preexisting brain changes on the therapeutic outcome and side effects from ECT. Pilot data suggest that these brain findings do not change during a course of ECT. The potential relationship of these brain changes to the development of affective disorder in the elderly is discussed and areas for future research are suggested.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

Few procedures performed under general anesthesia affect the heart as profoundly as electroconvulsive therapy (ECT). Considering the major disruptions of rate, contractility, conduction pattern, and myocardial repolarization that occur, the treatment's excellent safety record is surprising. The purpose of this review is to reassess the cardiac consequences of induced seizures. The physiological mechanisms activated during treatment will be examined, and from this the implications for clinical management will be discussed.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

A comparison of methohexital at 0.5 mg/kg versus 1 mg/kg iv as anesthesia for unilateral brief pulse electroconvulsive therapy showed no difference in systolic or diastolic blood pressure before, immediately after, or 5 or 10 min after the seizure. Mean seizure duration was not significantly shorter using the higher methohexital dosage. These results show that methohexital can be safely used in a broad dosage range without undue effects on blood pressure or seizure duration.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

Nineteen patients with major depression were alternately given intravenous atropine or saline immediately prior to anesthesia for electroconvulsive therapy (ECT). Atropine increased the heart rate, reduced the number of dropped beats, and reduced the number of premature atrial beats. These features may be advantageous in patients with cardiac hypodynamic states presenting for ECT, that is, with bradycardia, bradyarrhythmia, or hypotension. However, as atropine also increased the cardiac work, we recommend that it not be given to patients with hypertension, tachycardia, or who are at risk for cardiac ischemia.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

The occurrence of undesirable events during the postictal electro-convulsive therapy (ECT) period was retrospectively compared between 29 patients who had received glycopyrrolate premedication 0.002 mg/lb i.v. and 25 patients who had received atropine 1.0 mg i.m. A separate comparison was made for 14 patients who had received ECTs with each of these premedications. A total of 952 ECTs were reviewed. In both comparisons supraventricular tachycardia was more common with atropine (p< .0001 with each), after —13% of ECTs. Otherwise, postictal events with the two agents were indistinguishable; specifically, bradycardia and nausea were not more frequent with glycopyrrolate.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

The authors review the results of electroconvulsive therpay (ECT) in 135 cases of depression occurring in conjunction with organic dementia, subcortical leukoencephalopathy without dementia, and depressive dementia (22 cases). Overall, 86% had a positive therapeutic response to ECT, whereas 21% experienced significant cognitive or memory side effects, virtually all of which were transient and reversible. Forty-nine percent of the patients with organic or depressive dementias experienced improvement in cognitive or memory function consequent to ECT.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID