ISSN:0036-5521    

DOI:10.3109/00365527809179799

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

Secretin (1 CU/Kg) plus Caerulein (100 ng/Kg) or Cholecystokinin (1 or 21vyU/Kg) were given by rapid intravenous injection (Schedule 1) or by continuous infusion (Schedule 2) to 63 control subjects (C) and 69 patients affected by chronic pancreatitis (CP). Duodenal juice was collected for two and four 30-minute periods in schedule 1 and schedule 2, respectively. Volume, bicarbonate, and enzyme content were measured. Secretin-Caerulein, by rapid intravenous injection, showed a strong overlapping between C and CP values and led to some side-effects. Secretin-Caerulein by continuous intravenous infusion gave almost identical results as the Secretin-Cholecystokinin

ISSN:0036-5521    

DOI:10.3109/00365527809179800

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

The angiographic appearance of the portal vein in the dog before and after major hepatic resection is described. An increased diameter and length of the lobar vein and their ramifications were found following resection. The appearance both in the portal and sinusoidal phase indicated a diffuse growth of the liver remnant. One week after resection a portal hypertension was recorded, which had usually receded after six weeks. Major hepatic resection seems to imply a higher risk for fatal toxic effects from the contrast medium.

ISSN:0036-5521    

DOI:10.3109/00365527809179801

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

Total and selective hepatic vein angiographies were performed preoperatively and 6 weeks after 70 per cent liver resection in 6 dogs. The alterations in the hepatic vein system, increased diameter and elongation of the remaining lobar veins and their major tributaries plus increased angle between the radicles, are consistent with the findings earlier described by angiography of the hepatic arterial and portal venous system after major hepatic resection in dogs.

ISSN:0036-5521    

DOI:10.3109/00365527809179802

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

The effects of giving atropine, pentazocine or pethidine, 30-45 minutes before intravenous diazepam have been assessed and compared with a control group given diazepam alone in a double-blind controlled trial of pre-medication for upper gastrointestinal endoscopy involving 143 patients and 6 endoscopists. Atropine or pentazocine increased the success rate of the procedure (p 0.007) but gave no other definite benefit. Pethidine improved the degree of sedation (p 0.01) and the success rate (p 0.007); the combination of pethidine given before diazepam ranked first of all the four treatment regimes. The patients' opinion of the procedure correlated with the duration of endoscopy and the experience of the endoscopist.

ISSN:0036-5521    

DOI:10.3109/00365527809179803

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

Serum immunoreactive gastric inhibitory polypeptide (IR-GIP). gastrin (IRG), and insulin (IRI) were estimated in 41 normal weight patients with duodenal ulcer (DU) and 25 age-matched controls in response to a high caloric liquid test meal. 28 out of 4 1 DU patients had a hyperglycaemic glucose response during the test meal, and 15 had a pathological oral glucose tolerance test. Fasting and food-stimulated IR-GIP and IRG levels were significantly elevated in the DU patients. Serum IRI also increased to significantly higher levels in DU patients after the test meal. The degree of the greater hormone response was dependent on the glucose increase after the test meal in the case of insulin and GIP. but not in the case of gastrin. It is concluded: firstly, that a faster glucose absorption (possibly due to rapid initial gastric emptying or increased intestinal motility) is responsible for the high and short-lasting glucose peak and the increased GIP and insulin secretion; secondly, that the GIP response could well be causally related to the insulin response; thirdly, that hyposcretion of GIP is ruled out as a possible factor in the pathogenesis of gastric acid hypersecretion of duodenal ulcer patients.

ISSN:0036-5521    

DOI:10.3109/00365527809179804

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

An experimental model is described which is intended to simulate and accentuate the movement of fluids across the intestinal mucosa resulting from simple small intestinal obstruction as well as to provide a means for measuring these fluid shifts. Working on the hypothesis that the increase in fluid in the obstructed small intestine is a consequence of increased osmolality resulting from enzymatic breakdown of the intestinal contents, a solution of high osmolality was introduced into an intestinal segment of known size and position. Under these conditions the intestinal mucosa functioned in the manner of a semipermeable membrane and permitted only fluids of low osmolality to enter the intestinal lumen, thus tending to normalize its hyperosmolal contents. The process of dilution followed a simple dilution curve. At the same time hemoconcentration and increased serum osmolality reflected the mobilization of fluids from the extravascular and vascular compartments. The transfer of fluids into the intestinal lumen continued throughout the test period, despite the fact that there was a linear increase in intraluminal pressure to a relatively high level, indicating increased smooth muscle tone probably due to the hyperosmolal provocation. The observed accumulation of fluid was well reproducible and associated with predictable effects on the vascular and extra-vascular compartments.

ISSN:0036-5521    

DOI:10.3109/00365527809179805

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

β-Sitosterol, administered in doses of 12 g/d, resulted in a mean decrease of 11% in serum cholesterol and of 12% in biliary cholesterol saturation after 6-8 weeks. Sustained effects were found in some individuals treated for longer periods. Significant changes in bile acid kinetics could not be detected. The results lend support for further investigations of sitosterol as a possible adjunct therapy in cholelitholytic treatment.

ISSN:0036-5521    

DOI:10.3109/00365527809179806

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

Giant pseudopolyposis is uncommon and only one obstructive case has previously been reported. In that case the underlying disease was ulcerative colitis while the present case seemed associated with Crohn's disease. Clinically this condition imitates a malignant tumour, and because of the rarity we failed to reach the right preoperative diagnosis in spite of correct colonoscopy and biopsy findings.

ISSN:0036-5521    

DOI:10.3109/00365527809179807

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

A decreased capacity of the leucocytes to phagocyte yeast particles was found in patients with Crohn's disease of the ileum. Patients with lesions only in the colon showed normal phagocytic activity as did patients with ulcerative colitis (U.C.). Intradermal injection of killedStrep, pyogenesproduced an increased erythematous reaction after 48 hours in patients with U.C., and the reaction was pustular in half of them. None of the controls or the patients with Crohn's disease of the ileum had such a reaction. An increased erythematous reaction to streptokinase-streptodornase was also more common in patients with U.C. than in those with Crohn's disease and a control group. No such difference was seen to other bacterial antigens. The reactivity to kallikrein, prostaglandin E1, histamine or bradykinin did not differ from that of normal subjects.

ISSN:0036-5521    

DOI:10.3109/00365527809179808

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor