摘要:

The authors studied a series of 308 patients with temporal lobe tumours (265 intracerebral and 43 extracerebral). The incidence of epilepsy in intracerebral temporal tumours was 41%. Epilepsy occurred most frequently in oligodendrogliomas (84%) and astrocytomas (53%). In 39% of patients various types of epilepsy were noted in the onset period of the tumoural symptomatology, and in 19% of cases epilepsy was the 1st symptom of the disease. The main clinical aspect of the seizures was that of paroxysmal alteration of consciousness without complete loss of awareness. Sensory hallucinations occurred either as aura or as independent manifestations. The most common electroencephalographic aspect was that of focalized slow waves, revealing the existence of the tumour. Sharp waves were recorded in only 6% of cases with epilepsy. In extracerebral temporal tumours, epilepsy was encountered most frequently in the cases of meningiomas of the temporal fossa (70%).

ISSN:0014-3022    

DOI:10.1159/000114072

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

The clinical, electromyographic and electroencephalographic features in a case of presenile dementia associated with myoclonus and running a slowly progressive course are described. Photic-induced seizures occurred in spite of nonspecific background EEG changes, and in the absence of spontaneous seizures. A brain biopsy was consistent with the diagnosis of Alzheimer''s disease. The case is discussed with respect to the diagnostic problems of the association between presenile dementia and myoclonus. The need for routine photic stimulation in these patients is stressed.

ISSN:0014-3022    

DOI:10.1159/000114073

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

In this prospective study of 47 cases of posttraumatic amnesia, the patient population followed a bimodal distribution. In 20 cases, retrograde amnesia was of short duration and compatible with a failure of consolidation of the memory trace. Most patients in this group suffered a simple concussion. By contrast, all patients with rettrograde amnesia of long duration showed evidence of structural brain damage with persistent memory deficit, and their amnesia seemed secondary to failure of retrieval rather than failure of consolidation.

ISSN:0014-3022    

DOI:10.1159/000114074

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

Protein composition of myelin and white matter was analysed in 8 multiple sclerosis (MS), 2 sub- acute sclerosing panencephalitis and 1 postvaccinal leucoencephalitis autopsy samples. Special attention was paid to basic or encephalitogenic protein because its possible role in the pathogenesis of MS has been suggested by numerous authors. We found decreased quantities of encephalitogenic protein in MS myelin samples but on the other hand the proportion of basic protein was normal in SSPE myelin. However, when freeze-dried whole tissue samples were analysed the basic protein was decreased most in MS cases but also moderately in SSPE and leucoencephalitis. These results suggest a different mechanism in demyelination for MS and SSPE. The results of our earlier reports suggest early changes in glia cells and the loss of basic protein seems to be only one of the later features of MS.

ISSN:0014-3022    

DOI:10.1159/000114075

出版商:S. Karger AG    

年代:1971

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000228701

出版商:S. Karger AG    

年代:1899

数据来源: Karger

摘要:

In a series of 48 patients with myasthenia gravis the authors have determined in 14 instances muscle LDH activity, isoenzyme pattern, the MDH/LDH ratio, the percentual ratio of M subunits, and in 60 instances total serum LDH activity and isoenzyme pattern. Slight increase of serum LDH activity, decreased muscular LDH activity (with increased MDH/LDH ratio), increased serum LDH1, LDH2 and LDH3, the reduction of muscular LDH5 and M subunits are assumed to be the consequence of muscle atrophy accompanying myasthenia in some cases, or of myositis and/or myopathy complicated by myasthenia. In pure myasthenia without muscle damage, investigations did not show any difference, except that an increase of serum LDH3 isoenzyme was observed in over a third of the cases; the authors state their hypothesis concerning the origin of this increase.

ISSN:0014-3022    

DOI:10.1159/000114076

出版商:S. Karger AG    

年代:1971

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000114077

出版商:S. Karger AG    

年代:1971

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000228702

出版商:S. Karger AG    

年代:1899

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000228703

出版商:S. Karger AG    

年代:1899

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000228704

出版商:S. Karger AG    

年代:1899

数据来源: Karger