摘要:

This paper reports on 294 patients with presumptive symptoms of epilepsy but no noteworthy, or only suspicious, EEG findings. With recording during sleep after 24–27 h of sleep deprivation, 138 persons showed definite epilepsy potentials. The remainder of the group showed no noteworthy findings. Nevertheless, on the basis of clinical observations and the course of the patient’s illness, epilepsy was diagnosed in 27 patients of this second group. Neurophysiological aspects of the electroence phalographic provocation method are discus

ISSN:0014-3022    

DOI:10.1159/000114656

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Two patients sustained an ischemic brain stem infarction during medical examination and treatment. The first patient lost consciousness and the spontaneous respiration ceased during X-ray examination of the cervical spine when the neck was hyperextended. After some minutes he regained conciousness but was found to be tetraplegic, and the patient deceased 4 months later. The angiogram revealed thrombosis of the basilar artery. The other patient had profuse nosebleed and was treated with posterior tamponation during which she sat for about 10 min with the neck hyperextended. Some hours after this procedure symptoms and signs of lateral caudal brain stem infarction emerged.

ISSN:0014-3022    

DOI:10.1159/000114657

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Three cases were observed with the same substantial clinical features: flexion contracture of the third, fourth, and fifth finger and less extensive of the wrist. The contracture appeared after a mechanical injury not related to the involved muscles. In two cases the lesion was situated above or in the elbow region, in the third on the ulnar border of the forearm. In all cases there were some ulnar nerve signs and symptoms but the contracture involved flexor muscles which were co-innervated by the median nerve. The signs and symptoms improved or disappeared entirely after neurolysis. The question is raised, whether the contracture is due to peripheral nerves damage.

ISSN:0014-3022    

DOI:10.1159/000114658

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

The effect of thoracic duct lymph drainage (5–34 days) in 12 patients with myasthenia gravis on muscular function has been followed for 5–43 months. Among the results obtained were: (1) During the drainage the myasthenic symptoms decreased markedly after 1–4 days and remained so during the drainage. (2) The doses of cholinesterase inhibitors had to be markedly reduced during the lymph drainage in eight patients. (3) Discontinuation of the lymph drainage increased the myasthenic symptoms within a few days. However, after a median observation time of 14 months with conventional treatment all but one of the patients had improved. (4) Retransfusion of the patients own cell-free lymph caused a worsening of the myasthenic symptoms. This effect could also be obtained following infusion of IgG preparations from the patients lymph. Three retransfusions of cell suspensions obtained from the thoracic duct lymph from two patients had no effects on their myasthenic symptoms. (5) It is suggested that thoracic duct lymph drainage can be combined with other forms of treatment in severe cases of myasthenia g

ISSN:0014-3022    

DOI:10.1159/000114659

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000219438

出版商:S. Karger AG    

年代:1903

数据来源: Karger

摘要:

A comparison has been made of the localization and ontogenetic development of acetyl-cholinesterase (AChE) and succinic dehydrogenase (SDH) in sections of fetal human spinal cord and brain stem using histochemical methods. Spinal cord sections of young fetuses (8–10 weeks in utero) showed low to moderate enzymatic activity whereas sections of older fetuses (12–18 weeks in utero) revealed high concentrations of AChE and SDH in the ventral and lateral horns. A similar increase in enzymatic activity during development was also observed in brain stem sections where AChE and SDH were mainly confined to cranial nerve nuclei. A comparison of our histochemical findings with investigations on the development of motor activity in the spinal cord suggests that there is a correlation between the increase in AChE activity and functional developm

ISSN:0014-3022    

DOI:10.1159/000114660

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000219439

出版商:S. Karger AG    

年代:1903

数据来源: Karger

摘要:

Myotonia-like activity was recorded from various muscles of rats treated with 25-azacholesterol for a period of 2–8 weeks. 50% of myotonic rats showed a decline of amplitude of the evoked muscle potentials of the flexor digitorum muscle on stimulation of the median nerve with supramaximal stimuli at frequencies of 3, 5, 8, 15 or 50 cps. Administration of prostigmine increased neuromuscular failure. This temporary paresis of myotonic muscle resembles the transient impediment of motility of myotonic patients and it is entirely different from myasthenic transmission defec

ISSN:0014-3022    

DOI:10.1159/000114661

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Report on quantitation of IgG in cerebro spinal fluid (CSF) and serum of 84 children at different ages. A relation was shown between the content of IgG in CSF and serum depending on age. The decrease of the ratio CSF-IgG/serum-IgG as well as of the total protein in the CSF during the first trimenon points out a post partal impediment of the diffusion from the blood to the CSF compartment. Beyond the first year of life the ratio of the concentrations mostly remains constant. Measurements in 135 children suffering from several neurological diseases showed that quantitation of IgG is of value only in case of suspicion of encephalitis with local synthesis of IgG.

ISSN:0014-3022    

DOI:10.1159/000114662

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000219440

出版商:S. Karger AG    

年代:1903

数据来源: Karger