摘要:

In order to investigate whether sleep deprivation activates the photoconvulsive response 35 patients were investigated electroencephalographically after 24–36 h of waking. In 34 cases with sleep deprivation photostimulation showed a clear photosensitivity which was not present before sleep deprivation. This pathological response to photostimulation was unchanged after the short sleep period, in some even potentiated. Long-term anticonvulsive therapy could not suppress the positive photic reaction after sleep deprivation. No correlation between the blood glucose level and photosensibility could be determined. In summary it can be stated that sleep deprivation appears to have a activating effect on photosensitivity. The clinical employment and the neurophysiological mechanisms are discusse

ISSN:0014-3022    

DOI:10.1159/000114301

出版商:S. Karger AG    

年代:1974

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000220958

出版商:S. Karger AG    

年代:1902

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000220959

出版商:S. Karger AG    

年代:1902

数据来源: Karger

摘要:

Three patients with cortical blindness resultingfrom simultaneous ischemia of both occipital lobes are presented. In all cases there was clinical and/or angiographic evidence of basilar artery occlusion. Visual agnosia was present in all three patients. The cortical blindness was completely transient in one case, partially transient in the second, and permanent in the third. The pathogenesis of the simultaneous loss of both visual half-fields in basilar artery occlusion is discussed and compared with the bilateral homonymous hemianopia resulting from successive, bilateral occlusions within the internal carotid arterial systems.

ISSN:0014-3022    

DOI:10.1159/000114302

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

The electrophoretic evaluation of the cerebrospinal fluid (CSF) proteins was performed in the cutis verticis gyrata and mental retardation (CVG-MR) syndrome, as the assumed handicapped CSF circulation might result in an altered electrophoretic pattern. In seven patients with the miscellaneous form of the syndrome the electrophoretic findings did not deviate significantly from the normal. In nine patients with the primary form’ of the syndrome there was a significant increase in α1-globulin (p<0.05) and β-globulin (p<0.01) fractions as well as a decrease in albumin fraction (p<0.05). The ratio between albumin and globulins was 1.5 in the primary group and 1.8 in the miscellaneous group. In the primary group the total amount of β-globulins was 66 mg/1 and in the miscellaneous 46 mg/1 (p<0.05). Consequently, CSF electrophoresis may serve as a diagnostic clue for the primary form of the syndrome, which appears to be a separate condition of its

ISSN:0014-3022    

DOI:10.1159/000114303

出版商:S. Karger AG    

年代:1974

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000220960

出版商:S. Karger AG    

年代:1902

数据来源: Karger

摘要:

The patients with Parkinson’s syndrome and multiple sclerosis show lower levels of HVA in CSF than most other patients. The latter group also has low levels of 5-HIAA. Hydrocephalus is generally supposed to have high 5-HIAA. Our study with normotensive hydrocephalus shows that these patients have normal levels. Decrease in HVA is found in spinal cord lesions with restricted flow, as has been pointed out by Curzon et al. Low values of 5-HIAA are seen in patients with transverse lesions presumably due to disappearance of the spinal portion of 5-HIA

ISSN:0014-3022    

DOI:10.1159/000114304

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

The present paper describes a family showing the association of a neuropathy and a nephropathy with a gastropathy, as well as deafness and ocular changes (cataracts and vitreous opacities), which is similar to a family described by Van Allen et al. This provides evidence that a recently described third type of primary amyloidosis is a clinical entity in itself.

ISSN:0014-3022    

DOI:10.1159/000114305

出版商:S. Karger AG    

年代:1974

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000220961

出版商:S. Karger AG    

年代:1902

数据来源: Karger

摘要:

Our study includes assays of the serum activities of ALD, CPK and GOT and GPT transaminase in a patient with McArdle’s disease. Muscle glycolysis has been investigated and the glycogen concentration and phosphorylase activity determined biochemically in the muscle biopsy. Our results point to three major biochemical features which are indicative of McArdle’s disease: in the blood, the failure of venous lactic acid to rise after ischaemic exercise, and in the muscle the increase of glycogen concentration and the lack of phosphorylase activ

ISSN:0014-3022    

DOI:10.1159/000114306

出版商:S. Karger AG    

年代:1974

数据来源: Karger