ISSN:0014-3022    

DOI:10.1159/000213456

出版商:S. Karger AG    

年代:1906

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000213416

出版商:S. Karger AG    

年代:1906

数据来源: Karger

摘要:

7 brains out of a series of 124 necropsies of treated leukemic patients show a communicating hydrocephalus, without invasion of the central nervous system by the malignant blood cells. In 4 cases it is proven that the hydrocephalus is due to obstruction of the liquor drainage at the level of the arachnoidal villi and dural sinuses, by the leukemic invasion of these structures. It is shown that, even in case of preventive brain irradiation and intrathecal-administered cytotoxic drugs, these structures remain areas, in which the leukemic cells are difficult to destroy.

ISSN:0014-3022    

DOI:10.1159/000115047

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

Cerebrospinal fluid metabolites of dopamine, norepinephrine and serotonin were studied in two groups of left temporal lobe epileptic patients, the only difference between the two groups being that one group had paranoid schizophrenic symptomatology. Homovanillic acid accumulation was decreased in this group. This finding may be a biochemical indicator of a genetic predisposition to schizophrenic symptomatology in certain epileptic patients.

ISSN:0014-3022    

DOI:10.1159/000115048

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

A case of involuntary plantar flexion of the toes and sole with no other neurological pathological sign is reported. The electromyographic activity of some muscles of the involved limb, the behavior of the phenomenon during the sleep-wakefulness cycle and spinal reflex excitability have been studied. According to the clinical and neurophysiological findings, the phenomenon appears to be a dystonia. Such a dystonia may occur as the only pathological neurological sign or together with other signs of central nervous system involvement. Particular care has to be taken to distinguish ‘tonic foot’ from hypertonus of sole flexor muscles occurring almost always in all spastic hemipare

ISSN:0014-3022    

DOI:10.1159/000115049

出版商:S. Karger AG    

年代:1979

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000213457

出版商:S. Karger AG    

年代:1906

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000213418

出版商:S. Karger AG    

年代:1906

数据来源: Karger

摘要:

The action of intravenously injected taurine, glycine and GABA has been tested on convulsions induced by strychnine using electroencephalographic and electromyographic recordings. The dose of strychnine necessary to produce a generalized tonic-clonic seizure was 0.55 ± 0.15 mg/kg intravenously for rabbits pretreated with taurine, which was significantly higher than for control animals (0.38 ± 0.13 mg/kg). After pretreatment with glycine, the strychnine dose required to evoke convulsions (0.51 ± 0.22 mg/kg) was also higher than the control values, but the difference was statistically not significant. The convulsive dose of strychnine in animals pretreated with GABA was slightly but not significantly lower than in control animals (0.31 ± 0.13 mg/kg). These results suggest that taurine is the most effective amino acid to protect rabbits from seizures induced by strychn

ISSN:0014-3022    

DOI:10.1159/000115050

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

16 patients with multiple sclerosis, complaining of urgency, frequency and urge incontinence were studied urologically. They all suffered from detrusor hyperreflexia. We managed to improve this disturbance by lowering the parasympathetic tone and at the same time increasing the sympathetic tone of the urinary outlet, using a combination of imipramine and propantheline. The subjective clinical alleviation was also corroborated by cystomanometry and urethral pressure profile before and after treatment.

ISSN:0014-3022    

DOI:10.1159/000115051

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

2 patients with hypoparathyroidism, one idiopathic and the other pseudoform, were studied by overnight polygraphic recording of the sleep EEG and related activities before and after start of treatment to investigate their sleep EEG patterns and stages, with the results as follows. (1) Conspicuous abnormalities were noted in the sleep record, namely, disappearance of humps, spindles and hill waves, emergence of the mitten pattern and rather monotonous delta rhythm bursts. The EEGs, both awake and asleep, showed findings suggestive of a possible disorder of the desynchronizing mechanism of the brain stem. Normal sleep EEG patterns were restored after the serum calcium level had returned to the normal range. (2) In the course of overnight sleep, disturbance in the cyclic changes of sleep EEG pattern and absence of REM sleep were observed. Restoration to the normal course of sleep was achieved following the normalization of serum calcium level. Divalent calcium ion is considered to have intimate bearing upon the mechanism whereby synaptic chemical transmitters are activated. When viewed with reference to the monoamine hypothesis of Jouvet, the disturbance in the course of sleep observed in the present cases, especially the absence of or disturbed REM sleep, is inferred to be related to the hypocalcemia.

ISSN:0014-3022    

DOI:10.1159/000115052

出版商:S. Karger AG    

年代:1979

数据来源: Karger