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1. |
Morphologic Aspects of the Neurofibrosarcoma (Neurogenic Sarcoma) |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 1-10
O. Vuia,
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摘要:
Two cases of malignant tumours of the nerve sheaths are reported. In the first patient, who had von Recklinghausen’s disease, light- and electron-microscopic investigations showed an undifferentiated mesenchymal tumour of the radial nerve with the property of producing collagen fibres, an aspect characteristic of sarcoma of the fibroblastic type. In the second case a pleomorphic cell sarcoma of the cranial nerves of the left cerebellopontine angle was present. The morphologic aspects of these tumours show them to be primary mesenchymal tumours of the nerve (neurofibrosarcoma, neurogenic sarcoma), originating in the fibroblastic-like elements of the nerve sheaths. The clinical and nosologic framework of this type of malignant tumour of the nerve sheaths is discusse
ISSN:0014-3022
DOI:10.1159/000114873
出版商:S. Karger AG
年代:1977
数据来源: Karger
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2. |
Acute Pure Vertiginous Dysequilibrium in Cerebellar Infarction |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 11-15
Rodolfo L. Guiang, jr.,
Owen B. Ellington,
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摘要:
A clinical example of an acute cerebellar infarct mimicking an acute end-organ labyrinthine disease is reported to foster general familiarity with the simulation of a benign disorder by a potentially serious one. The utility of certain neurologic findings in distinguishing a peripheral from a central vestibulo-cerebellar disorder is discussed.
ISSN:0014-3022
DOI:10.1159/000114874
出版商:S. Karger AG
年代:1977
数据来源: Karger
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3. |
Myasthenia gravis: Steroid-Induced Effects on Lymphocyte Subpopulations in Myasthenia gravis |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 16-22
L. Hammarström,
E. Smith,
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摘要:
Lymphocyte subpopulations from patients with myasthenia gravis were evaluated during chronic steroid therapy. A marked lymphocytopenia (10–70%) was initially (day 3–21) noticed as well as a preferential depletion of thymus-derived cells which parallelled the clinical deterioration. Thus there was a relative increase in B cells, although their absolute numbers remained rather constant. These changes were reverted within 2–4 weeks in spite of continuous treatment. These findings are compatible with a release of myasthenic factors (anti-acetylcholine receptor antibodies?) during the initial steroid-induced cell damage, the long-term beneficial effects being due to loss or suppression of autoreactive helper T
ISSN:0014-3022
DOI:10.1159/000114875
出版商:S. Karger AG
年代:1977
数据来源: Karger
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4. |
Superior Orbital Fissure Syndrome |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 23-30
Gian Luigi Lenzi,
Cesare Fieschi,
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摘要:
Superior orbital fissure syndrome is a symptomatologic complex, consisting of retro-orbital pain, paralysis of extraocular muscles, impairment of first trigeminal branches and frequent involvement of the optic nerve. From a review of 130 published cases including two personal observations, it appears that the clinical subdivisions and the several eponymic differentiations of this syndrome are unjustified on the basis of etiologic, therapeutic and prognostic elements. Only the presence – or absence – of optic signs may allow to hold the clinically useful distinction between the often ‘benign’ superior orbital fissure syndrome without optic nerve involvement, and the orbital apex syndrome where orbital exploration may be recommended. This review concludes that repeated neurosurgical and neuroradiologic investigations – with the exceptions of carotid angiography and orbital phlebography – can be avoided in
ISSN:0014-3022
DOI:10.1159/000114876
出版商:S. Karger AG
年代:1977
数据来源: Karger
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5. |
Karyometric Changes in Human Muscle with Age |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 31-34
D. Vassilopoulos,
E.M. Lumb,
A.E.H. Emery,
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摘要:
Human muscle cell growth was studied to investigate the nucleo-cytoplasmic ratio during development and ageing. The mean muscle fibre size, as well as the number and size of myonuclei were estimated in human muscle biopsies from normal individuals whose ages ranged from 1 to 71 years. Changes in muscle fibre size were accompanied by similar changes in nuclear number, the size of which remained the same. This resulted in a constant nucleo-cytoplasmic ratio during the age range studied. The role of the satellite cell in the maintenance of this ratio was discussed.
ISSN:0014-3022
DOI:10.1159/000114877
出版商:S. Karger AG
年代:1977
数据来源: Karger
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6. |
Neuromyotonia |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 35-41
S. Negri,
T. Caraceni,
A.B. Boiardi,
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摘要:
The authors report the case of a 67-year-old man, affected by diffuse spasms evoked by ischemia and voluntary and reflex movements, electromyographically characterized by an intense repetitive activity. There was also a modest and diffuse muscle wasting, with lower limbs areflexia; no myokymia. The EMG showed severe neurogenic changes and a considerable reduction of the MMCV in the lateral popliteal nerve area.
ISSN:0014-3022
DOI:10.1159/000114878
出版商:S. Karger AG
年代:1977
数据来源: Karger
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7. |
Pharmacology of Huntington’s Chorea |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 42-50
T. Caraceni,
P. Giovannini,
F. Girotti,
G. Avanzini,
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摘要:
Dipropylacetic acid (DPA), γ-aminobutyric aicd (GABA), physostigmine, CB 154 and butyrophenones were administered to 26 patients affected by Huntington’s chorea. The evaluation of the pharmacologic activity of the different drugs was determined by means of some clinical parameters and motor performance tests. Butyrophenones succeeded to ameliorate the hyperkinesias and the motor dexterity, CB 154 provoked a worsening of the motor signs of the disorder, while DPA, GABA and physostigmine did not modify the clinical pattern. The relationship between these results and the Huntington’s chorea physiopathology is discussed and a hypersensitivity of DA receptors is sugge
ISSN:0014-3022
DOI:10.1159/000114879
出版商:S. Karger AG
年代:1977
数据来源: Karger
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8. |
Moderate Nonketotic Hyperglycemia – a Cause of Focal Epilepsy |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 51-61
J.J. Askenasy,
M. Streifler,
R. Carasso,
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摘要:
Nonketotic hyperglycemia has a definite convulsive effect, which may manifest itself in generalized or focal seizures. This report deals specifically with focal convulsive phenomena. Two patients with nonketotic hyperglycemia focal seizures are described. Focal seizures are of motor Jackson, aphasic, adversive or of the ‘epilepsia partialis continua’ type. Different types of focal seizures may appear in one and the same patient. Focal epilepsy can be the first manifestation of a diabetic disorder. Focal epileptic seizures are linked with moderate nonketotic hyperglycemia with values of 360 mg% sugar and 310 osm. Higher values lead to generalized seizures and coma. The mechanisms are discussed and pertinent literature is revie
ISSN:0014-3022
DOI:10.1159/000114880
出版商:S. Karger AG
年代:1977
数据来源: Karger
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9. |
Glycolytic Substrate Utilization and Energy Consumption in the Cerebral Hemispheres of the Mouse during Experimental Anuria |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 62-68
Ldszló Szegedy,
Johan F. Jongkind,
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摘要:
The glycolytic substrate utilization and energy consumption of hemispheres of adult mice were studied by converting the heads into a closed system by decapitation. It was concluded that progressive insufficiency of renal function is parallelled by an increase in brain permeability for glucose and a progressive reduction in brain energy metabolism.
ISSN:0014-3022
DOI:10.1159/000114881
出版商:S. Karger AG
年代:1977
数据来源: Karger
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10. |
Renal Clearance of Pyridostigmine in Patients with Myasthenia gravis |
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European Neurology,
Volume 16,
Issue 1-6,
1977,
Page 69-72
K. Chan,
T.N. Calvey,
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摘要:
The urinary clearance of pyridostigmine was studied in six patients with myasthenia gravis. In three patients on pyridostigmine alone, renal clearance ranged from 349 to 481 ml/min, corresponding to a pyridostigmine:creatinine clearance ratio of 2.64 to 3.46. In a patient on bendrofluazide as well as pyridostigmine, a similar clearance ratio was observed. By contrast, the urinary clearance of pyridostigmine and the pyridostigmine creatinine clearance ratio was reduced in two myasthenic patients concurrently treated with other basic drugs. It is suggested that these results may reflect competition for renal tubular excretion.
ISSN:0014-3022
DOI:10.1159/000114882
出版商:S. Karger AG
年代:1977
数据来源: Karger
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