摘要:

SUMMARY.—Case studies of 2 patients with bullous skin lesions are reported, one of whom also had thyrotoxicosis and rheumaloid arthritis, and results of serological tests for the “pemphigus” antibody in 92 patients with other immunopathies. The “pemphigus” antibody, which reacts with the intercellular substance of squamous epithelium, was demonstrable in 1 case at low titre before the onset of widespread skin lesions; titres correlated with the activity of the skin lesions of pemphigus vulgaris; and the antibody was detected at low titre in diseases other than pemphigus vulgaris, including myasthenia gravis (2 cases) and systemic lupus erythematosus (1 case). The possible clinical and serological overlap between pemphigus vulgaris, myasthenia gravis and systemic lupus erythematosus was interpreted from the standpoint of thymic dy

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14189.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—Four patients with pemphigoid have been followed clinically and serologically for a sufficient period to indicate that pemphigoid antibody titre does not necessarily parallel the clinical activity of the disease. In contrast, for pemphigus, there does seem to be such a correlatio

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14190.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—Two patients suffering from erythropoietic protoporphyria who died from liver failure with jaundice and portal hypertension are presented. The hepatic lesion was characteristic—a micronodular cirrhosis with massive deposits of protoporphyrin. The term erythrohepatic protoporphyria is preferred to erythropoietic protoporphy

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14191.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—Two cases of cutaneous lymphocytoma associated with solar urticaria and polymorphic light eruption are reported and the results of phototesting described. These results suggest that the action spectrum in each case was probably dependent on the type of associated photodermatosis and not on the lymphocytoma. The relationship between lymphocytoma, “actinic reticuloid” and the lymphocytic response to phototesting is disc

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14192.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—A patient with skin lesions, which were corrected by folic acid therapy, is described. The probable explanation for the skin manifestations is discusse

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14193.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—The coefficient of friction has been determined for skin and various materials. It has been established that the behaviour of skin is not portrayed by the simple laws of friction, but by a more complex relationship of the type F =μWn. This is probably because skin is subject to viscoelastic rather than purely plastic deformation. Friction may be altered by the type of material in contact with skin and is further influenced by surface lubrication. Dry talcum powder reduces friction slightly for certain materials against skin, but increases friction when it becomes wett

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14194.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—The nucleoside triphosphatase activity of epidermal Langerhans cells was studied in autolytic skin. Enzyme activity could be seen up to 2 days in specimens incubated at 37° C. and up to 26 days in specimens incubated at 4° C. It is pointed out that this histochemical staining method seems to be very stable and not confined to a special and transitory functional state of this cell system. It is concluded that this method could possibly be used as a marker for the identification of Langerhans cells underin vitroconditi

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14195.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—Six patients with vasculitis and cryoglobulinaemia have been investigated. In all but 1 the cryoglobulins were of the mixed variety. On immunofluorescence of the acute vasculitis lesions deposits of immunoglobulins of the same classes as those found in the cryoglobulins were detected in 4 patients; other immunoglobulins not present in the cryoglobulin were additionally present in 2 of the 4 and no or only weak deposits were present in 2. Fibrin and complement were found in all.The pathogenesis of vasculitis in cryoglobulinaemia is discusse

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14196.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—The skin‐window technique was applied to normal und involved skin sites of 17 patients with mycosis fungoides, 8 patients with parapsoriasisen plaque, and 6 patients with cutaneous lymphomata, and also to normal skin of 25 controls. Large mononuclear cells rapidly migrated in large numbers from plaques of mycosis fungoides and parapsoriasis. Identical cells were seen in skin windows from control sites at later intervals. No malignant cells were found in any of the skin windows of mycosis fungoides or purapsoriasis. Malignant cells were found in cases of malignant cutaneous lymphoma. Comparison of cells found on the skin windows from mycosis fungoides plaques to lymph node imprints indicates that the former are immature reticular cells without neoplastic features. We conclude that mycosis fungoides is a proliferation of these benign immature reticular cells in the s

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14197.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—The water vapour loss from irritated and non‐irritated skin sites was determined twice daily during a period of 19–42 days after the irritation. Diurnal variation of skin temperature gives anomalous values for water vapour loss but does not account for anomalous activation ene

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14198.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY