ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb15405.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb15406.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY

摘要:

Summary.—Recent work on the bacteriology of acne is reviewed with particular reference to the role of antibiotics in treatmen

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb15407.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY

摘要:

SUMMARY.—Disseminated elastosis perforans is described in 4 mongoloids. The natural evolution of the disorder in 3 of these patients has produced linear and retiform scars. Recognition of this quela will facilitate diagnosis when dtypical grouped or annular hyperkeratotic papules are no longer presen

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb01885.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb15408.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY

摘要:

SUMMARY.—The literature on the turnover or renewal time of normal and psoriatic epidermis is critically reviewed. It is concluded that the time taken by a cell to travel to the surface, once it has been formed, is probably 40‐56 days in normal skin, and 6‐8 days in psoriatic

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb01886.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY

摘要:

Summary.—The cutaneous diphtheroids have very varied morphological and biochemical characters which make grouping for ecological studies difficult. Several schemes have been proposed and are discussed. For convenience, the organisms are divided into lipophilic and non‐lipophilic diphtheroids, those producing porphyrins, those with some keratinolytic ability and the anaerobic diphthero

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb15409.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY

摘要:

SUMMARY.—The method of skin surface biopsy in which a cyanoacrylate adhesive is used to remove a coherent strip of stratum corneum, has been used to investigate aspects of epidermal function. The Sudan dyes were employed to demonstrate sebum in the hair follicle openings. Although increased quantities of Sudanophilic material were detected with increasing time intervals before sampling, it proved impractical to measure sebum secretion quantitatively by this method. Hydrolase activity in and around hair follicle orifices of the back, forehead and forearm were demonstrated, using enzyme histochemical methods for non‐specific esterase, acid phosphatase, leucine aminopeptidase and β‐glucuronidase activities. Specimens from the forehead and back were found to have stronger activities than those from the forearm. Apart from the vicinity of the follicular openings, non‐specific esterase activity was not normally found in the superficial stratum corneum, although scattered areas of activity were present in the deeper parts of the horny layer. Strong, non‐specific esterase activity was detected in skin surface biopsies from lesions of pityriasis lichenoides and, to a lesser extent, those of psoriasis. Mitochondrial enzyme activities were retained in parakeratotic scale from patients with psoriasis, pityriasis rubra pilaris and areas made parakeratotic after repeated removal of the stratum corneum, although not from the lesions of pityriasis lichenoides. The method also proved suitable for the demonstration of melanin granules, blood pigment and sweat glan

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb01887.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY

摘要:

Summary.—As a result of experience of staphyococcal cross‐infection in conventional dermatology wards, various changes in the design and practices of dermatology wards, have been studied.Decentralization of treatment to the patients' rooms in place of a special treatment room in the ward may have reduced the colonization of patients with hospital strains of staphylococci, but did not influence the rate of clinically manifest infections.Strict isolation of disseminators of pathogens and of patients especially prone to infection, significantly reduced the colonization rate with hospital strains of staphylococci. Isolation of patients on systemic steroid or cytostatic treatment, patients with erythroderma, extensive eczemata or extensive bullous dermatoses and heavy disseminators ofStaph. aureusor streptococci is recommen

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb15410.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY

摘要:

SUMMARY.—Epithelial cells from adult guinea‐pig and human skin were grown in monolayer culture and studied by phase contrast and electron microscopy. Significant differences were found between cellsin vivoandin vitro.Keratinocytes show a selective dedifferentiation. They retain the ability to make desmosomes, but interdigitation is reduced and the system of tono‐filaments is disorganized. Mitochondria become long and even branched‐while microtubules become prominent, as do lysosomes and fat droplets. Ribosomes often become arranged in polyribosomes. and channels appear in the nucleus. Melanocytes showed similar changes, and 1 produced a cilium.Such changes should be taken into consideration when cells in dispersed culture are used experim

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1972.tb01888.x

出版商:Blackwell Publishing Ltd    

年代:1972

数据来源: WILEY