摘要:

Abstract.In order to evaluate electrical parameters of gross response electro‐myograms, the interrelationship between the integrated electric activity and the number of motor impulses of the myograms obtained from human forefinger abductor muscle in voluntary, non‐isometric contractions was studied. The integrated activity was determined by planimetry. The number of motor impulses were counted irrespective of location and size. The relationship between the integrated activity and the number of motor impulses was found to be linear in contraotions up to a spike frequency of 500 cps. It was concluded that, as far as small muscles are concerned, counting of the motor impulses in the electromyogram, recorded with non‐selective electrodes, can be used in estimating the electric activity of the whole m

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01680.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY

摘要:

Abstract.The effect of various lower aliphatic aloohols on the accumulation of formaldehyde in rat liver homogenates incubated with methanol has been studied. The addition of ethanol inhibited very clearly the accumulation of formaldehyde, n‐propanol, isopropanol or n‐butanol had no effect on the accumulation of formaldeh

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01681.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY

摘要:

Abstract.The formation of formaldehyde from methanol in liver homogenates was almost totally abolished in molybdenum‐deficiency induced by tungstate feeding. The addition of diphosphopyridine nucleotide, adenosine triphosphate or xanthine was not able to increase the formation of formaldehyde from methanol in the molybdenum‐deficient liver homogenates as it did in normal homogenates. The utilisation of added formaldehyde was also depressed in the molybdenum‐deficient homogenates. The liver xanthine oxidase activity fell to very low values after the feeding of tungstate, but the catalase activity of liver was not affected

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01682.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY

摘要:

Abstract.The influence of some specific group inhibitors on rat intrinsic factor was studied in order to elucidate the nature of the active structure of intrinsic factor. Iodine and fluorodinitrobenzene inhibited both the vitamin B12‐‐binding capacity and the physiological intrinsic factor activity, whereas p‐chloromercuribenzoate anddiisopropylfluorophosphate lacked effect on either activity. The results add further evidence in favor of the concept that intrinsic factor contains an essential structure which binds B12, and that a phenolic group may be involved in this stru

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01683.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY

摘要:

Abstract.Some modifications in the fluorimetric method of Eulerand Flodingare described. The urine sample, usually 25 ml, is adjusted to pH 8.2–8.3 and passed through a column of aluminium oxide. The catechols are eluted with acetic acid, neutralized with ammonia to pH 6.2–6.3, oxidized with potassium ferricyanide and transformed to stable lutines with alkali and ascorbic acid. The fluorescence of the lutines is read with two filter sets and the amounts of adrenaline and noradrenaline compu

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01684.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY

摘要:

Abstract.The effects of two crystalline fractions of prostaglandin (PGE and PGF) were tested on a variety of isolated organs and on the blood pressure of the rabbit. Characteristic differences in the activity ratio for PGE and PGF were noted for different organs. The biological actions of partially purified preparations of prostaglandin could be largely but not wholly explained by assuming that they contained a mixture of PGF and PGE.

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01685.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY

摘要:

Abstract.Chemically pure prostaglandin E was infused in doses of 0.2–4.7 μglkglrnin in two healthy male subjects over periods of 4–10 min. Tachycardia, reddening of the faoe, headache and an oppressive feeling in the chest were noted. Systemic arterial blood pressure and cardiac output fell modera

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01686.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY

摘要:

Abstract.If diamine oxidase is allowed to act upon the diamine putrescine, a cyclic compound, δl‐pyrroline, will be formed, which in turn reacts with o‐aminobenzaldehyde to form a yellow compound. These reactions have been taken as a starting point for a photometric method for determination of diamine oxidase. If a solution containing o‐aminobenzaldehyde, putretrcine and a diamine oxidase preparation is incubated at 37° C a characteristic yellow colour is obtained. The intensity of the colour can be measured spectrophotometrically. The influence of pH and of the concentration of putrescine and o‐aminobenzaldehyde on the reaction has been tested. The wavelength which gives a maximal extinction has been determined. The variation of the extinction with increasing time of incubation has been studied. On the basis of these investigations a standard procedure is suggested. Simultaneously determinations of diamine oxidase in different dilutions have been carried out using this colorimetric method and the Warburg

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01687.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY

摘要:

Abstract.Zinc‐induced relaxation in glycerol‐extracted rabbit psoas fibre bundles was studied under strictly iso‐tonic and isometric conditions and compared with the effects of zinc on the visco‐elastic behaviour of resting fibre bundles subjected to quick stretch. 0.a mM zinc + 1 mM magnesium + 0. 4 mM ATP does not affect the visco‐elastic properties but induces relaxation of isometrically and isotonically contracted fibre bundles. Isotonic relaxation is complete only when the previous shortening does not exceed 25 percent of initial fibre length; the relaxing effect is practically absent when the bundle has shortened about 75 percent of its initial length. 2 mM zinc + 1 mM magnesium + 6 mM ATP and 4 mM EDTA + 4 mM magnesium + 4 mM ATP, which markedly decrease the visco‐elastic resistance in the fibre bundle produces a pronounced isotonic relaxation even after extreme shortening of the bundles. Thus, the isotonic relaxation of glycerol extracted fibre bundles is dependent upon a decrease in the visco‐elastic resistance. The isometric relaxation, on the other hand, does not need any pronounced visco

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01688.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY

摘要:

Abstract.It has previously been established that 20–100 mg of polyunsaturated oils given daily to young rats raised on a 1 % cholesterol—10 % hydrogenated coconut oil diet results in a pronounced reduction of the serum cholesterol concentration. By means of extraction of the serum lipids, chromatographic separation, and alkali isomerization it has now been shown that this decrease in serum lipids, reflected in reductions in both free and esterified cholesterol and in non‐cholesterol lipids, is accompanied by characteristic changes in the polyenoic fatty acid composition of the cholesterol esters. Linoleste supplementation resulted in the appearance of more dienoic and tetraenoic acid in the esters, linolenate particularly in the appearance of pentaenoic, but also some hexaenoic acid. Cod liver oil had an effect on all polyenoic constituents, and the magnitude of this effect, referred to the actual content of such acids in the oil, was by far the strongest. This indicates a preference in the organism for the ready made polyunsaturated acids. The largest reductions in total cholesterol were correlated with a preponderance of lino‐lenic acid‐type unsaturation in the esters, a fact which emphasizes the relative inferiority of linoleic acid in the aspect of cholesterol metabolism her

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1959.tb01689.x

出版商:Blackwell Publishing Ltd    

年代:1959

数据来源: WILEY