摘要:

Summary.Alcoholic extracts of whole blood from cattle and normal human subjects produce a rise of blood pressure and tachycardia in the cat, after adsorption of depressor constituents with Fuller's earth. The active substance is inactivated by iodine in neutral or slightly alkaline solutions.The pressor action is enhanced by cocaine, and inhibited or abolished but not reversed by a dose of dihydro‐ergotamine sufficient to reverse the action of an equipressor amount of adrenaline.The evidence presented supports the assumption that the normally occurring pressor agent in bovine and human blood is chiefly nor‐adrenaline (sympathin).The amount of sympathin found in bovine and human whole blood corresponds to some 2–4 μg dl‐nor‐adrenaline hydrochloride per 100 ml blood.This work has been supported by a grant from the Rockefeller Foundation to one of us (U. S. v. E.) which is gratefully ac

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00396.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

Summary.The content of vitamin K, chlorophyll, carotin and xantho‐phyll was determined in the following plant organs: 1) leaves of closely related plants with different synthetization of chlorophyll, 2) leaves and roots of plants with iron deficiency chlorosis, 3) leaf areas of panached leaves, and 4) leaves in which the pigments were in various phases of break‐down. The results do not indicate that there is any simple correlation between the synthesis and break‐down of vitamin K and the various leaf pig

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00397.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

Summary.A constrictory action of some bile acids on cat's and guinea‐pig's bronchi is describe

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00398.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

Summary.Rabbits have been poisoned by the inhalation of hydrogen cyanide in air or in oxygen. Signs of failing cardiac activity have been chosen as the indicator of the status ante mortem. Insufflation of pure oxygen in this stage saves the subject's life.The experiments have confirmed the earlier assumption that the hydrogen cyanide poisons the respiratory centre, which leads secondarily to the anoxia that is the immediate cause of death. Oxygen treatment is therefore more rational and more rapid in its effect than the methods based upon detoxication of the hydrogen cyanide.

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00399.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

Summary.The authors have endeavoured to adapt the classical method of extirpation, for investigating the function of a tissue, to the lymphoid system. Operative technique for the removal of lymphoid organs is described for use on guinea‐pigs and rats.In rats we found a pronounced lymphopenia lasting for three to six weeks in association with the operations. In the first days it was found to be unspecific, whereas during the remainder of the period it stands presumably in causal relation to the extirpatio

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00400.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

Summary.In a dialyzed casein hydrolysate (Aminosol), produced by the hydrolysis of casein with trypsin and erepsin 76 per cent of the peroral preparation and 67 per cent of the intravenous one is composed of free amino acids.In this dialyzed casein digest the following amino acids occur in a free form viz. alanine, arginine, asparaginic acid, glutamic acid, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophane, tyrosine, valine.The investigation showed that the ten esseltial amino acids, arginine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophane, and valine, occur in the free form, a fact which, chemically speaking, proves that this dialyzed casein digest is an adequate source for the nitrogen needs of the body.

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00401.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

Summary.The rate of accumulation of radio‐active sodium in the aqueous humour of the rabbit is not appreciably influenced by the blood pressure reduction caused by occlusion of the common carotid artery. If sodium had entered the aqueous by ultrafiltration, a material reduction of the rate of entrance would have occurred. Consequently sodium does not enter the aqueous by ultrafiltration but mainly by secretio

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00402.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

Summary.1. The phosphorus turnover of the pineal has been studied with the aid of radioactive phosphorus in rats of different ages and compared with the turnovers of the adenohypophysis, neurohypophysis, tuber cinereum and cerebellum. The activities in these organs with exception of cerebellum are lowest during the first 10 weeks of the life of an animal. In the fertile age the activity remains at a constant high level and with exception of the neurohypophysis increases somewhat during senility. The activity of the cerebellum remains unchanged.2. Of the 42 organs and parts of the brain investigated, the phosphate metabolism decreased only in the ovaries after epiphysectomy to a statistically probable extent. Considerable increases in the turnover were also observed in the adenohypophyss, neurohypophysis and tuber cinereum in females.3. After castration an increased phosphorus turnover was obtained in the pineal body and the adenohypophysis. This increase was most pronounced in females.4. It appears to follow from these results that the pineal exerts an influence, directly or indirectly, especially upon the ovaries. There appear to be reciprocal effects of a similar nature between the ovary and the epiphysis as between the adenohypophysis and the ovaries.We wish to express our thanks to Professor Manne Siegbahn for his kindness in placing radioactive phosphorus at our disposal.

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00403.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

Summary.Experiments on the cat show that β‐dimethylaminoethyl benzhydryl ether hydrochloride (2–10 mg/kg) depresses salivary secretion induced by chorda and sympathetic stimulation and by injection of acetylcholine and pilocar

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00404.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

Summary.β‐dimethylaminoethyl benzhydryl ether hydrochloride in a dose which strongly antagonises the effect of histamine on the motility of the gut has no antihistamine action on gastric secretion in cats under chloralose. On the contrary there is an increase in the rate of secretion. This may possibly be due to the fact that the drug itself slightly stimulates gastric secreti

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1947.tb00405.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY