ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00672.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Book review in this article:Paediatric Dermatology and Dermatopathology Vol 1.R Caputo, AB Ackerman and EQ Sison‐Torr

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00673.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

SummaryIn Australia, dermatologists have been designated as the soleprescribers of isotretinoin*and thus we are in a unique position to audit national usage of the drug. Questionnaires were sent by the Australasian College of Dermatologists to all 204 practising Fellows in Australia. The aim was to study the number and type of patients treated with isotretinoin, the manner in which the drug is prescribed, adverse reactions and the number of pregnancies occurring during and after treatment. Judging from the 85% of questionnaires which were returned, isotretinoin is an effective and welt‐tolerated drug for the treatment of severe nodulocystic acne. In the five years that isotretinoin has been used in Australia, U pregnancies while taking the drug were reported. These pregnancies occurred despite exhaustive counselling by dermatologists and the patients being fully aware of the risks to the fetus and the need for adequate contraceptive measures. With one exception, all agreed to have a therapeutic abortion. There were two reports of congenital abnormalities after cessation of treatment, neither of which were thought to be related to isotretinoi

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00674.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

SummaryIsotretinoin is a well‐established, effective treatment for severe nodutocystic acne. An important consideration which may limit the prescription of isotretinoin is its cost. Based on a literature review, we have compared isotretinoin with the conventional combination of antibiotics and topical therapies for the treatment of severe nodulocystic acne in terms of cost and benefit. Our results show that when duration of treatment is considered, isotretinoin is cheaper and significantly more effectiv

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00675.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

SummaryThe prevalence of use of sunscreens was assessed in an environment of high ultraviolet (UV) exposure by surveying U7 males and 126 females on two Queensland beaches. Using a questionnaire, information was obtained about their application of sunscreen on the day of participation in the study, thus eliminating recall error. It was found that 71% of the female and 68% of the male beach‐goers sampled had applied sunscreen, 47% of which had the maximum Sun Protection Factor (15 +) rating. There was no significant association found between usage and either skin colour or socio‐economic status. Although 88% used a waterproof formulation, only 61% reapplied the sunscreen directly after swimming. Sunscreen was not applied to all exposed body parts, with over half of the subjects neglecting ears and lower limbs. Reported major reasons for use were to avoid skin cancer (44%), and to avoid sunburn (43%). The results of this study can assist in evaluating the effectiveness of present sun‐protection campaigns in the short

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00676.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Book review in this article:Clinical DermatologyJAA Hunter, JA Savin and MV Dahl.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00677.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Book review in this article:Methods for Cutaneous Investigation(Volume 9, Cosmetic Science and Technology Series), Robert L. Rietschel and Thomas J. Spencer (Eds).Sunscreens: Development, Evaluation and Regulatory Aspects(Volume 10, Cosmetic Science and Technology Series), Nicholas J Lowe and Nadim A Shaath (Eds).

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00678.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

SummarySeventy‐seven skin biopsies diagnosed histologically as lentiginous junctional naevi from individuals aged over 60 years were reviewed. Seventy‐three specimens showed a primarily nested pattern with disordered arthitecture concentrated within the rete ridges conforming to the pathology of a lentiginous dysplastic naevus. In 28 biopsies this was combined with a melanoma in situ. The latter was reflected by a focal loss of the rete ridge system, confluent melanocytic hyperplasia and single cell invasion of the epidermis by atypical malanocytes. Four biopsies showed lentiginous junctional naevi with only isolated naevus cell nests without a disordered architecture or cellular atypia. Thirty‐seven of the 57 naevi in men were located on the back in contrast to 5 of the 20 women. In women the lower limb was the most frequent site with 8 of the 20 lesions originating at this site in contrast to 1 of the 57 men. The pathological diagnosis of dysplastic lentiginous naevi in the elderly needs to be recognised as having a high association of melanoma‐in‐sit

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00679.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Book review in this article:Lecture Notes on Dermatology. 6th EditionR Graham‐Brown and T Burns.Handbook of Dermatology. 1st EditionDJ Barke

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00680.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

SummaryA review of consecutive biopsies from 85 Malaysian patients with primary localized cutaneous amyloidosis (PLCA) revealed 63 with papular amyloidosis (PA) and 22 with macutar amyloidosis (MA). PLCA appeared to affect the Chinese more frequently than the other major ethnic groups but MA was more common than expected among the Indians. Of patients with PA, one had systemic lupus erythematosus, one scleroderma and in another, connective tissue disease was suspected. MA was not found to be associated with any other disease.Histologically, PA differed from MA by the larger size of amyloid deposits in the papillary dermis. There was no difference in their tinctorial and immunohistochemical characteristics. Deposits were permanganate‐resistant and negative for AA protein, immunoglobulin light chains and keratin. A few cases exhibited positively for cytokeratin. Strong immunoreactivity for AP protein was observed. PA and MA appear chemically similar and are likely to be of epidermal origi

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1991.tb00681.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY