摘要:

This survey was performed by the Japanese Pathological Society and briefly reported at the 9th Conference of the International Society of Geographical Pathology. The materials consisted of 12,430 autopsies in colleges and several main hospitals in Japan. The number of cases with myocardial infarction was 817 (6.57%) in total, but 670 (6.10%) among 10,976 autopsies were examined further in detail. The incidence of cases with larger manifest infarction was 338 (3.08%) of 10,976 autopsies. The incidence of cases with myocardial infarction was found to be far less in Japan than in Europe and America. The incidence of both moderate and severe coronary sclerosis (G1 and G2) was considerably low (the frequency of C2 was 12.14%), while that was far higher in cases with myocardial infarction (64.5%). The frequency of coronary thrombosis in cases with manifest infarction was 29.9%, while that in non‐manifest one 3.0%. There were 191 cases with myocardial infarction regarded as the cause of death (28.5% of 670 cases), the majority of which, 183, belonged among cases with manifest infarctio

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1970.tb01207.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Of recent years the cells proliferating in the intima of obliterating endarteritis which is noted in stomach ulcer have been concluded to be connective tissue consisting of fibroblasts. The present author observed electron microscopically seven lesions of obliterating endarteritis at various stages obtained from six cases of chronic stomach ulcer and found that the proliferating cells were all characteristically modified smooth muscle cells. There was no evidence that the cells are either fibroblasts, pre‐existing fibroblasts, maturation of immigrating mononuclear inflammatory cells or endothelial cells. The smooth muscle cells played the leading part in obliterating endarteritis as in intimal thickening due to arteriosclerosis. The arterial smooth muscle cells have many functions such as production of collagen fibers, elastic fibers and basement membrane as well as accumulation of lipid. In conclusion, it may well be said that the arterial smooth muscle cells play the most important role in the pathogenesis of vascular lesions of small arteries including inflammatory lesions morphologicall

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1970.tb01208.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Amyloidosis of the liver, lymph nodes and spleen were induced in high frequency in the rabbits and mice sensitized with antigen‐antibody complex, HGG‐antiHGG complex, or heat denatured DNA (Calf thymus, SIGMA Co.).The fine structural changes of the spleen were similar to those in the other experimental models previously reported.Concurrent systemic vasculitis in these animals suggested the possibility of a disturbed immune mechanism as a common causative backgro

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1970.tb01209.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Whole HeLa cells supravitally stained with Janus green B were irradiated with ruby laser light, in order to injure mitochondria selectively. For light microscopic observation, NADH dehydrogenase activity was used as a marker for mitochondria. Immediately after irradiation, the cells stained for NADH dehydrogenase activity showed small vacuoles outlined with the enzyme reaction product and punched‐out lesion in cytoplasm, distribution of which corresponded to that of mitochondria in control cells. Electron microscopic observation of irradiated cells disclosed electron opaque particles in mitochondrial matrix and varying sized vacuoles in mitochondria. The light and electron microscopic changes were confined within the mitochondria at the optimum conditions of the dye concentration and the laser light intensity. On morphological bases, it was concluded that mitochondria were selectively injured by the combination of Janus green B supravital stain and ruby laser light irradiatio

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1970.tb01210.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

At autopsy of a 60‐year‐old male, the authors found two malignant tumors occurring in different organs. One was hepatocellular carcinoma originating in the right lobe of the liver, and the other was leiomyosarcoma occurring in the right retroperitoneal space. They collided at the edge of the right lobe of liver and mixed together. The mixed area showed structures of true carcinosarc

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1970.tb01211.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Ewing's sarcoma originating from the 2nd lumbar vertebra, found in an autopsy case of a 12‐year‐old girl was investigated histologically and electron microscopically. The distinguished features of neoplastic cells of this case were phagocytosis, desmosomes, and abundant glycogen in their cytoplasm. The origin of neoplastic cells is assumed to be immature reticulum ce

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1970.tb01212.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

The present paper is a clinicopathological study of three cases of rhabdomyosarcoma originating from relatively unusual sites, in the neck, heart and peritesticular region. A review on the frequency of the original site for 114 cases of rhabdomyosarcoma reported in recent Japanese literatures revealed 3 originating from the neck (2.6%) 2 from the heart (1.8%), and 2 from the peri‐testicular region (1.8%

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1970.tb01213.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

The second autopsy case of microlithiasis alveolaris pulmonum in our country was discussed. This case had no familial back‐ground or genetic predisposition for the disease and followed an almost asymptomatic course for 13 years since abnormal shadow of chest was revealed radio‐logically.Of interest in this case in the deposition observed microscopically of the same substance in alveolar walls or in the interstitium as the ground substance of intra‐alveolar microlith, which was probably responsible for the irregular elas

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1970.tb01214.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

The present authors have studied the reticulum cells of the spleens in bacterial infectious cases with the silver impregnation method which was improved for the purpose of investigating reticuloendothelial cells. On the impregnated sections, the splenic reticulum cells were divided into the following four types; (1) branching, (2) polymorphic, (3) round, and (4) foamy. The polymorphic and round cells were considered to be branching types activated or mobilized. The polymorphic and round cells increased in the spleens of the infectious cases, except in those cases showing exhaustion of vital reaction.

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1970.tb01215.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY