摘要:

Ferric chloride and human thrombin solutions, either individually or mixed, were introduced into the right ventricle or into the auricular veins of 73 rabbits, and the subsequent changes in the pulmonary vessels and auriculer viens were examined by means of light and electron microscopy. Platlet plugs (pseudothrombi) formed immediately after the treatments are aggregation of platlets with apparently intact cell membranes and could be differentiated from the arethentic thrombi in that in the latter there was fibrin invasion of the endothelial cells. Release of the alpha granules from the platlets played a great role in fibrin formation and appeared to occur without disruption of the cell membranes. The endothelial cytoplasms were invaded by fibrin in an early phase of thrombosis and injury to the endothelial cells probably act as a trigger to the further development of the thrombi. So thrombosis pogressed, the platlet cytoplasms were also invaded by the fibrin. As an initiating factor in the development of thrombosis the author emphasizd the role of increased coagulability. ACTA PATH. JAP. 16:1‐36, 19

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01937.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

One hundred fifty‐four hearts were examined by postmortem coronary arteriography including ordinary and soft x‐ray exposure of the sliced hearts. Serial giant frozen sections of the entire heart were made to obtain the topographic view and quantitative observation of the ischemic lesions of the myocardium in connection with underlying changes of the coronary tree as well as electrocardiographic findings.Anatomical characterisitcs of the coronary arteries such as tortuousness and right angle ramification of the myocardial branches running toward cardiac lumen were demonstrated. Their endarteric nature at the level of functionally efficient terminal zone of the myocardial branches was pointed out and its important role in the development of ischemic lesions was discussed. The reason why the inner layers of the myocardial wall possesses much disadvantage of coronary circulation was clarified from the aspects of morphological findings and on some physiological considerations.The clinicopathological survey of the. cases indicated that the patients with hypertrophic hearts and coronary sclerosis are most vulnerable to the development of myocardial injury. The disadvantages of the hypertrophic state of the heart in the coronary circulation were emphasized.It was concluded that the myocardial injury is directly proportional to hypertrophy, hypertension, heart rate and coronary sclerosis. Based on the tension theories of the hypertrophic heart, the conclusion was theoretically confirmed to be reasonable. Myocardial injury index was suggested for practical use. ACTA PATH. JAP. 16:37‐54

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01938.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

The clinicail and pathological data of twin brothers suffering from presumably congenital hepatosplenomegalies with liver cirrhosis, congestive spleens, mental deficiency, and discoloration in retinae and papillae are reported. The etiological causes are discussed in relation to congenital metabolic disorders in children. ACTA PATH. JAP. 16:55‐68, 19

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01939.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

An autopsy case of so‐called florid cirrhosis is firstly presented in Japan.Brief clinical records, major gross and microscopic findings are described. This peculiar type of hepatic disease was characterized by a history of alcoholism and malnutrition, severe hepatic degeneration and necrosis with Mallory bodies, diffuse but irregular proliferation of membraneous connective tissue and spotty fatty metamorphosis.A case at AFIP filed as typical “florid cirrhosis”, and 3 cases of diffuse “interstitial cirrhosis” in Mexico were carefully studied histologically to help for the diagnosis and analysis of the inducing process of this disease. ACTA PATH. JAP. 16:6

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01940.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

Friend virus‐induced tumor cells do not always require the presence of Friend virus for continued growth. A line of non‐virus producing (NVP) Friend tumor cells was established, but it still induces some antigens which will neutralize the Friend virus. The characteristics of this antigen were described. ACTA PATH. JAP. 16:79‐95

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01941.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

A case of primary acquired agammaglobulinemia is reported. This case provided a valuable chronological observation of lymphoreticular and hematopoietic tissues and other organs. The cause of diffuse fibrosis and increase of hyaline material in various organs is discussed. ACTA PATH. JAP.16:97‐108, 19

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01942.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

1) Eighteen cases with definite thymic lymph follicles were found among 1,356 autopsies. Eight of those were cases of Basedow's disease and the remaining 10 consisted of 2 cases of asthma syndrome one of which was associated with a type of allergic granulomatous angiitis, 1 case each of Wegener‐like granulomatosis, periarteritis nodosa, rheumatoid arthritis, aplstic anemia, chronic glomerulonephritis, acute yellow liver atrophy, Ekiri syndrome and purulent necrotizing tracheo‐bronchitis.2) No morphological differences were found between the thymic lymph follicles and lymph follicles in other organs. The folliculated thymus did not indicate any specific morphological features.3) Basically, in cases with thymic lymph follicles, the lymphatic tissue of other organs showed lymphatic follicular hypoplasia.4) Speculative explanation of the histogenesis and significance of thymic lymph follicle formation was attempted. ACTA PATH. JAP. 16:109‐130

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01943.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY