摘要:

This communication deals with a type of chest pain which is not uncommon, and which is likely to lead to an erroneous diagnosis of coronary arterial disease. The term "hypercyanotic angina," which has been applied to the syndrome in the past, is unfortunate because many of the patients are not cyanotic, and further because the physiologic mechanism of the pain, while still obscure, appears to be different from that of the pain of angina pectoris. In the patients we have observed, the one constant feature other than pain has been clinical evidence of increased pressure in the pulmonary vascular circuit. Hence, the term "pulmonary hypertensive pain" is employed, but with the reservation that more complete knowledge of the exact pathogenesis may make a different name desirable.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID

摘要:

The effect of thevetoidin in heart failure has been studied. Thevetoidin has a prompt and partly transient digitails-like effect which is shown on the heart rate, the circulatory velocity and on the P-R and Q-T intervals of the electrocardiogram, and also a cumulative effect similar to that of strophanthin. Due to its intense vagal effect and its quick digitails-like action, paroxysmal auricular tachycardia was stopped in two patients out of three in from three to four minutes. Its therapeutic advantages and disadvantages are discussed.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID

摘要:

Hexamethonium by subcutaneous injection in doses of 10 to 75 mg. of the ion every 8 or 12 hours produced significant reductions of arterial pressure and symptomatic improvement in a high percentage of patients with benign or malignant hypertension. Methods for preventing tolerance and undesirable side effects are presented, and the advantages as well as the limitations of hexamethonium therapy are discussed.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID

摘要:

The compound 1-hydrazinophthalazine appears to be be an antihypertensive drug of only moderate potency. Based on experience with 50 cases of arterial hypertension, it was found most effective in patients with unsuccessful sympathectomy, malignant hypertension, and neurogenic hypertension. It was relatively ineffective in renal hypertension and in a group of miscellaneous conditions. Chronic administration by mouth in outpatients was feasible.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID

摘要:

A Valsalva-like maneuver was performed during cardiac catheterization by a normal group of individuals and a group of patients with acoustic evidence of mitral stenosis. The latter group was subdivided according to its response to the maneuver. The mild group, like the normal group, showed an "overshoot" of blood pressure and a bradycardia in the post-straining period, whereas the severe mitral stenosis group did not. The relatively undisturbed dynamics of the mild mitral stenosis group, in contrast to the marked disturbance in the severe group, was felt to be due to the amount of obstruction at the mitral valve. Additional data from the cardiac catheterizations of these patients is presented to substantiate this concept. This simple maneuver may prove to be a bedside method for the evaluation of the dynamic significance of mitral stenosis.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID

摘要:

Thirty-eight direct electrocardiographic records have been obtained by applying an exploring electrode directly to the epicardium after incision of the pericardium in the case of seven patients subjected to thoracotomy for various forms of heart surgery. These cases include three individuals with the tetralogy of Fallot, one with mitral stenosis, one with coarctation of the aorta, one with probable pulmonary atresia and one with a patent ductus arteriosus. This exploration has permitted us to study the patterns obtained in different regions of the right and left ventricular epicardial surfaces in four patients with right ventricular hypertrophy, two patients with left ventricular hypertrophy, and one patient with a heart whose left ventricle-right ventricle ratio was probably little disturbed.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID

摘要:

The clinical course was observed and balance studies were conducted in a series of patients with congestive heart failure who had hyponatremia and who had become refractory to mercurial diuretics. The data obtained during control periods and during treatment with hypertonic sodium solutions suggest that, in addition to sodium depletion, some disturbance is present in the mechanisms which regulate the water balance of the body. The administration of potassium did not appear to effect a diuresis.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID

摘要:

Changes in cardiac size, as measured by teleroentgenogram, in the course of essential hypertension were studied in 45 patients. Although the majority showed progressive cardiac enlargement from the discovery of hypertension, a goodly number revealed a stationary cardiac size for 10 or more years. Congestive heart failure was found to occur with normal heart measurements. Weight loss did not affect a reduction in cardiac size. Normal cardiac measurements for a decade or more were not unusual. Marked cardiac enlargement was present in several patients for 10 years with little functional limitation. Prognosis on the basis of cardiac size alone was unwarranted.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID

摘要:

In a two year period the effect of carotid sinus pressure on auriculoventricular conduction in a 70 year old man with angina pectoris increased markedly. At first, right carotid sinus pressure gave only P-R interval prolongation. Two years later, pressure on either side produced dropped beats. The maximum effect on the sinoauricular rate remained the same. No other change could be detected in the patient's heart during this period. The site of the cause of the increased vagal effect was either in the intrinsic cardiac nerves to the atrioventricular node or in the node itself.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID

摘要:

The electrolyte and water losses in 75 instances of diuresis following Mercuhydrin were studied in 17 edematous patients. The loss of potassium was appreciable following exhibition of the drug to patients who retained their dietary sodium almost completely. Occurrence of such clinical symptoms as weakness, nausea, and ventricular premature contractions might be attributed to this loss of potassium. The fluid lost by mercurial diuresis was isotonic with body fluids. The chloride concentration was fairly constant at 151 mEq. per liter. The concentrations of sodium and potassium were more variable, the average concentrations being 97 and 35 mEq. per liter, respectively. Loss of water and electrolyte in these concentrations leaves the patient in relative alkalosis, with a loss of intracellular potassium and a gain in intracellular sodium.

ISSN:0009-7322    

出版商:OVID    

年代:1952

数据来源: OVID