摘要:

It is the purpose of this paper to report the not too widely known clinical symptom of hip claudication and its relationship to aortic and iliac artery occlusions. The importance of aortography in the diagnosis of this syndrome is stressed and a technic is described. The results and findings differ from previous reports in the literature and these variations are discussed.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

Twenty-seven patients with clinically primary tuberculous pericarditis were treated with prolonged chemotherapy consisting of intermittent doses of streptomycin and daily doses of paraminosalicylic acid or isoniazid. Twenty-one patients did well and were symptom-free six months to three years later. Five, one of whom died, developed constrictive pericarditis. Another died of widely disseminated tuberculosis.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

As long ago as the middle of 1949 it had been demonstrated by the senior author that any blunt dilating mechanism applied within the stenotic aortic orifice would, upon expansion, force the separation of one or more of the fused commissures. Thus the diminutive valve orifice could be enlarged without the creation of additional insufficiency and with the restoration of such part of the original valve function as the pathologic distortion of the leaflets would permit. In other words the principles and effectiveness of such an aortic commissurotomy would be comparable to those of the similarly named operation for mitral stenosis. It has remained for us finally to develop an instrument and a technic capable of implementing these concepts, and this has at last been accomplished.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

Cation-exchange resins have not fulfilled early expectations. Those in clinical use do not retain much sodium in the feces when dietary sodium is much restricted. Comparison of the sodium and potassium bound by a resin, in equilibrium with presumably normal electrolytes as found in the terminal ileum, with the amounts of those ions in the feces, permits an over-all evaluation of two major factors operating in the gastrointestinal tract. These are a decreased sodium concentration in the terminal ileal contents when sodium intake is restricted and an absorptive power of the colon sufficient to detach sodium from the resin.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

A clinical study is presented of the influence of continuous intravenous norepinephrine therapy upon shock accompanying myocardial infarction. The significant reduction in immediate and eventual mortality rates usually associated with this condition are discussed. Complications are defined, and a possible first reported instance is presented of ventricular tachycardia developing in the presence of complete heart block during the administration of large doses of norepinephrine.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

One hundred patients suffering from sustained arterial hypertension were studied over a period of two years during which time the action of parenterally administered hydrogenated ergot alkaloids (Hydergine) constituted the main drug therapy. An immediate transient reduction of both the arterial blood pressure and the pulse rate was demonstrated in over 80 per cent of the entire group within a period of two hours. The average reduction in systolic and diastolic pressure was 36 mm. and 12 mm., respectively, and the pulse rate was reduced 6 beats per minute. Of interest was a group of 22 patients presenting evidence of early central vascular derangement in whom these alkaloids seemed to accomplish their best therapeutic action and possibly aborted what may have been a sustained cerebral accident. Untoward effects were minimal because of rapid dissipation of the drug, and its use in all types of hypertensive disease was deemed safe in the recommended dosage.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

For technical reasons, the measurement of cardiac output during brisk walking is difficult. By using a slight modification of the Hamilton dye-dilution method, such measurements, and measurements of mean circulation time, were made at rest and at the end of a moderate work load in normal subjects. A motor-driven treadmill was used for the exercise. It was found that the cardiac output increases 1.7 to 1.9 times and the mean circulation time decreases about 34 per cent in normal young men and women after a 10 minute walk at 3 miles per hour and 5 per cent grade.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

Blood flow to the extremities and kidneys was measured simultaneously in normal subjects, hypertensive patients and patients with obliterative arterial disease of the lower extremities. The latter group showed diminished basal flow in the lower extremities, increased basal flow in the upper extremities, and a delayed and diminished response to reflex heating, compared with the normal and hypertensive subjects. In all three groups, the increase in extremity blood flow was regularly accompanied by a concomitant decrease in renal blood flow. No significant change in arterial pressure was observed.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

The responses of the kidney and the lower extremities to single intravenous doses of six "hypotensive" drugs were measured in eight patients diagnosed as having essential hypertension. Use of Hexamethonium, Ilidar and Hydergine was followed by increase in the flow to the extremity and simultaneous decrease in renal blood flow. In contrast, the administration of Apresoline was followed by decrease in flow to the extremity and an increase in renal blood flow. Regitine produced no significant change in either. After the administration of protoveratrine, renal blood flow decreased but a significant change in blood flow to the extremity was not observed. Changes in arterial pressure which occurred with some of the drugs were not correlated with the changes in blood flow to the extremities or to the kidney.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

Priscoline can be given intra-arterially without difficulty. Untoward reactions are infrequent even in older patients. Intra-arterial administration was often effective in patients who did not respond to oral Priscoline. Although maximal vasodilatation may not be achieved by giving Priscoline intra-arterially, the degree of vasodilatation obtained is often adequate for a clinical effect. Results in 250 patients indicate that intra-arterial Priscoline is most useful in the treatment of ischemic rest pain resulting from organic vascular disease. Improvement in exercise tolerance was infrequent. Causalgia, delayed wound healing and ulceration in Reynaud's disease responded favorably in some instances.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID