摘要:

Although Hodgkin's disease is considered one of the “curable” cancers, the high cure rates associated with this disease are not accomplished without risk of potentially severe, immediate, and late side effects. Because the predominant histologic subtype of Hodgkin's disease found in the United States generally affects the 15- to 25-year-old age group, the disease, its treatment, and the side effects of treatment will affect many women of childbearing age. The treatment and its effects on the patient and offspring, including posttreatment fertility, are key issues for perinatal nurses

ISSN:0893-2190    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

As the incidence of human immunodeficiency virus (HIV) infection increases in women of reproductive age in the United States, clinical issues and therapeutic interventions specifically addressing the needs of HIV-positive pregnant women will continue to evolve and be incorporated into their obstetric care. This article provides perinatal nurse clinicians with an overview to the epidemiology and clinical manifestations of HIV infection in pregnant women, as well as the therapeutic modalities and psychosocial components included in their plan of care. Data regarding perinatal transmission rates and maternal factors possibly facilitating vertical transmission are also presented

ISSN:0893-2190    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

The diagnosis of breast cancer has a profound impact on women and their families. Although relatively uncommon, breast cancer associated with pregnancy is gaining attention as more women choose to delay pregnancy. The perinatal nurse must combine a knowledge of breast cancer and its treatment with an understanding of how this treatment will influence current and future pregnancies. Of critical importance are the roles of educator and patient advocate. This clinical review will discuss the natural history of breast cancer associated with pregnancy, its diagnosis and treatment, and the nursing implications for maternal and fetal care.

ISSN:0893-2190    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

This article combines data from two separate investigations. One study examined relationships between psychosocial factors and preterm milk immune variables. The other examined relationships between psychosocial and breastfeeding satisfaction factors and perceived milk sufficiency in term mothers. Milk samples were collected on the fifth postpartum day and frozen. Both studies collected data on anxiety, but other psychosocial variables differed. Mood states and social support were studied in preterm mothers, while breastfeeding satisfaction, milk maturation, and infant suckling characteristics were studied in term mothers. Milk samples were assayed for secretory immunoglobulin A (slgA) and cortisol. slgA and cortisol levels were higher in the milk from preterm mothers and were inversely related to each other in both preterm and term milk. In preterm mothers, anger and vigor were positively correlated with higher milk slgA. The findings suggest that cortisol is present in milk and may potentially influence the secretion of milk slgA. The relationships that were found when comparing psychosocial, dyadic, and stress factors with milk slgA and cortisol are provocative and suggest new paradigms for studying lactation

ISSN:0893-2190    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

The very-low-birth-weight (VLBW) infant is at high risk for developing infection during the antenatal, prenatal, and postnatal periods. The six major predisposing factors are perinatal infections, an immature immune system, decreased natural defenses, disease states and disorders leading to infection, side effects of medication, and prolonged hospitalization and iatrogenic complications of lifesaving therapies. Quality nursing care plays a crucial role in recognizing signs and symptoms of sepsis and facilitating a timely diagnostic evaluation. Prevention, prompt diagnosis, and treatment will reduce the high morbidity and mortality rates associated with sepsis in the VLBW infant

ISSN:0893-2190    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

Gene therapy is an innovative technique utilized in the treatment of a primary immunodeficiency known as severe combined immune deficiency syndrome (SCIDS). The first human trials of gene therapy for SCIDS were conducted in 1990, by attempting to insert the gene for adenosine deaminase into peripheral white blood cells to treat children with adenosine deaminase (ADA)- deficiency SCIDS. Recently, three infants with ADA-deficiency SCIDS received gene therapy with genetically manipulated hematopoietic stem cells. This clinical update reviews basic immunology function and malfunction, describes gene therapy, and specifically highlights hematopoietic stem cell gene therapy treatment for ADA-deficiency SCIDS

ISSN:0893-2190    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

The numbers of women and children infected with the human immunodeficiency virus (HIV) in the United States are growing rapidly. As these numbers increase, we can expect a strong impact on our health care system and our society as a whole. Research in the area of perinatal HIV is ongoing and of critical importance. Clinicians and hospital staff (as well as our communities) must be prepared to care for an ever growing number of newborns who are at risk for HIV infection. This article provides a review of the recent literature regarding perinatal HIV as well as a summary of the medical and psychosocial management of infants who are at risk for perinatally acquired HIV

ISSN:0893-2190    

出版商:OVID    

年代:1994

数据来源: OVID

ISSN:0893-2190    

出版商:OVID    

年代:1994

数据来源: OVID