摘要:

Lod scores for linkage of the albumin and Gc loci have been calculated for 21 pedigrees in which six different types of albumin variants are segregating. There is no evidence for heterogeneity in the linkage distance among the different types of variants. The most likely value for the recombination fraction in the combined data is at Ô = 0.023

ISSN:0001-5652    

DOI:10.1159/000152287

出版商:S. Karger AG    

年代:1970

数据来源: Karger

摘要:

Tongue pigmentation has been studied for testing the probable genetic mechanism determining this character. One pedigree from Kerala, and data on 132 families from West Bengal, have been reported here. Tests for segregation in the families support the genetic hypothesis that tongue pigmentation is an autosomal recessive character governed by two allelic genes, the ‘normal’ one being dominant over the ‘pigmented’. Detailed analysis of more data along with photographs of tongue pigmentation will shortly be pu

ISSN:0001-5652    

DOI:10.1159/000152288

出版商:S. Karger AG    

年代:1970

数据来源: Karger

摘要:

Studies of 20 children suffering from Down’s syndrome and of their parents have shown that the presence of thyroid autoantibodies was significantly more frequent in these children and in their parents than in the controls. Thyroid activity appeared to be normal in all cases of Down’s syndrome except for one child with mild hypothyroidism. Satellite association was found to be more frequent in cases of 21-trisomy (420 cells) than among controls (440 cells), but the difference was not significant. Satellite association with satellite approximation was, however, significantly more frequent in 21-trisomy. ‘G’ chromosomes were associated more frequently than ‘D’ chromosomes. The presence of thyroid autoantibodies had no effect on satellite association, either in cases of 21-trisomy or in healthy

ISSN:0001-5652    

DOI:10.1159/000152289

出版商:S. Karger AG    

年代:1970

数据来源: Karger

摘要:

The first African case of Waardenburg’s syndrome is described, presenting with the usual features of the syndrome, and in addition some features not reported befor

ISSN:0001-5652    

DOI:10.1159/000152290

出版商:S. Karger AG    

年代:1970

数据来源: Karger

摘要:

The frequency of colour blindness among the Jat males is 2.52% in Delhi and 4.53% in the Punjab. The difference between the Jats of the two areas is insignificant. The ratio protan (red blind) to deutan (green blind) type is 1:2.25 among the Jats of the Punjab, while all the affected males in Delhi were of the deutan type. The frequency of colour blindness among the Jats (Delhi and Punjab pooled together) is 3.53%. The protan:deutan ratio is 1:4. None of the females tested were found to be colour blind. The similarity of the Jats with most of the populations in North-Western India for the frequency of colour blindness indicates a considerable homogeneity in this region.

ISSN:0001-5652    

DOI:10.1159/000152291

出版商:S. Karger AG    

年代:1970

数据来源: Karger

摘要:

Bloodtyping was performed for 708 pairs of twins to establish zygosity. All pairs discordant on one or more factors were classified as dizygotic, and the results obtained from this DZ sample were tested against the expected distribution of concordant and discordant DZ pairs for each major blood group. There was close correspondence between expected and obtained values for all groups except Rh. Equations were developed for determining the probability that a concordant twin pair would be DZ rather than MZ. The method is illustrated for cases where the parents have also been bloodtyped, and for the more typical case where parental data are not available. In the latter case, there is about a 3% chance that a pair of twins who are concordant on all the major blood groups will be DZ.

ISSN:0001-5652    

DOI:10.1159/000152292

出版商:S. Karger AG    

年代:1970

数据来源: Karger

摘要:

The estimation of 6 or fewer objects (‘subitizing’) is considered to be a form of judgment which differs in speed and accuracy from the ‘estimation’ of 7 objects or more. In this study, 120 complete families (father, mother and one or more children), and a further 100 families lacking either father or mother, were asked to estimate the numbers of marbles or balls shown to them in transparent bags. The results indicate that there exist at least two phenotypes of judgment of numerousness: 1. subitizing of 6 marbles and 5 ping-pong balls, with high heritabilities; 2. estimation of 34 small, 15 small and 15 large marbles, with zero to low heritabilities, in the same population tested at the same time. The heritability estimates are based on parent: offspring correlations, corrected for assortative mating. Assortative mating was found for the 5 and 6 objects only. Father : son, mother : son, father : daughter, mother : daughter correlations were almost identical and gave no indication of differential maternal or paternal influences on estimation. Analyses of phenotypic distribution of offspring from different types of matings, based on under, over, and correct estimation, indicate that estimating two sets of less than 7 objects (subitizing) may be inherited on a polygenic basis while estimating sets of 15 or 34 objects shows low to no genotypic

ISSN:0001-5652    

DOI:10.1159/000152293

出版商:S. Karger AG    

年代:1970

数据来源: Karger

摘要:

On a sample of the Greek population, composed of 708 adult individuals (420 men and 288 women), G6PD types were studied by means of vertical electrophoresis. In addition to the common B type, three variants of the enzyme were found: (a) In one female, the rapidly migrating A type, the first to be described in a Caucasian subject; (b) In two males and one female, a slow variant, similar to the one described as Seattle variant; (c) In one female, a variant slower than the previous one, resembling the variant known as Austin I or Ibadan.

ISSN:0001-5652    

DOI:10.1159/000152294

出版商:S. Karger AG    

年代:1970

数据来源: Karger

摘要:

LDH isozymes were studied in human testes from prepuberal and mature aged individuals in monolayer testicular cultures, long-term cultivated seminal tubules, spermatozoa, seminal plasma, serum and erythrocyte hemolysate. The LDH-X fraction was found in spermatozoa, testes and cultivated seminal tubules at maturity in contrast to testes and monolayer testicular cultures from prepuberal individuals. LDH 5 was absent in spermatozoa and erythrocyte hemolysate. The authors are of the opinion that LDH-X fraction can serve as a biological enzymatic marker in human spermatozoa.

ISSN:0001-5652    

DOI:10.1159/000152295

出版商:S. Karger AG    

年代:1970

数据来源: Karger

摘要:

The relation between placental alkaline phosphatase phenotype and enzyme activity was examined in pregnancy sera and placental extracts from a series of about 400 deliveries. The results from electrophoretic examinations and quantitative measurements of pregnancy sera and placental extracts indicated that the activity attributable to the Pli1 allele was about half that of the Plf1 and Pls1-alleles.

ISSN:0001-5652    

DOI:10.1159/000152296

出版商:S. Karger AG    

年代:1970

数据来源: Karger