摘要:

Esterase-D phenotypes have been determined electrophoretically among the two regional groups of the Yanadi tribe of Andhra Pradesh in South India. The identified esterase-D2 (EsD2) gene frequencies among the coastal, interior and pooled Yanadis are 0.4320, 0.3562 and 0.3989, respectively.

ISSN:0001-5652    

DOI:10.1159/000153167

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

A method is given to resolve pleiotropy from linkage; to detect and estimate recombination free of incomplete penetrance, etiological heterogeneity, and other phenomena; and to estimate gametic frequencies for the main and test loci jointly. Large pedigrees, a liability indicator specifying risk groups (based on age, sex, or other factors), gametic disequilibrium, different recombination values in the two sexes, multiple alleles at the test locus, and a mixture of linked and unlinked marker loci are provided for. Parametrization of the marker locus is the same as for segregation analysis with pointers. The output includes standard errors, likelihood ratio tests of hypotheses, and a standard lod table for each sex separately. A model of closely linked complementing factors which can simulate recombination is also considered.

ISSN:0001-5652    

DOI:10.1159/000153168

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

Analysis of family resemblance in several bodies of data shows that about half of the variation in serum concentrations of IgM, IgA, and IgG is genetic. A substantial part of the remainder is due to twin shared environment, the effect of which is not significant for other relatives.

ISSN:0001-5652    

DOI:10.1159/000153169

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

1,004 unrelated Danes were typed for HLA-AB antigens and glyoxalase I (GLO), and investigations for linkage disequilibrium between the HLA and GLO loci were made using a maximum likelihood method for calculation of gene and haplotype frequencies. No linkage disequilibrium was found.

ISSN:0001-5652    

DOI:10.1159/000153170

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

In a study of genetic markers in patients with epilepsy, 30 genetic systems have been tested and the results compared with all previously published studies on this subjects. Only one marker, Ss + ss/SS in the MNSs blood group system showed a statistically highly significant difference (p below 0.001) in the epileptic patients compared with a control group. A previously reported difference in the Pc gene of the red cell acid phosphatase system was not confirmed in the present study. The basis for an association between the S antigen and epilepsy is difficult to understand at present and will need to be confirmed by studies on other groups of epileptic patients and in the aetiologically different groups before being accepted. This is especially so as the Chalfont patients are the only group so far studied for this blood group system.

ISSN:0001-5652    

DOI:10.1159/000153171

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

414 random samples of blood collected from unrelated male blood donors in Khartoum were analysed for erythrocytic glutathione reductase (GSR) phenotypes in relation to glucose-6-phosphate dehydrogenase (G6PD) and haemoglobin types by starch gel electrophoresis. The overall frequencies of GSR1 and GSR2 were found to be 0.9493 and 0.0507, respectively. The frequency of GSR° was very low (0.0241). The frequency of GSR2 was higher in G6PD-deficient subjects compared to normal subjects. GSR phenotypes were not related to the haemoglobin types. However, there was an excess of GSR° in subjects with haemoglobin A

ISSN:0001-5652    

DOI:10.1159/000153172

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

This paper describes a new antitrypsin variant unassociated with recognized disease or metabolic defects. We propose the designation of PiPsaintlouis (PiPstl) because the electrophoretic mobility of this variant is distinctly less than that of thePiPbudapest allele product, and greater than that of PiR. The variant (PiPstl) was transmitted from grandfather to father to two offsprings in the index family.

ISSN:0001-5652    

DOI:10.1159/000153173

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

Red cell glyoxalase I polymorphism was investigated in a population sample from the Strasbourg area. Gene frequency distribution in 337 unrelated subjects was GL01 = 0.455, GL02 = 0.545. There was no significant evidence of close association between GLOI asnd Bf phenotypes in a study carried out on 104 members of the population sample.

ISSN:0001-5652    

DOI:10.1159/000153174

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

Dermatoglyphic features of 200 male and 200 female normal Southern Nigerian negroes have been analysed. The frequency distributions of fingerprint patterns, digital and total ridge counts TRC, a–b scores and atd angles are given. In common with other races, the Southern Nigerian population showed the tendency for females to have more arches than males. Like the Zulus of Southern Africa, Southern Nigerian Negroes showed a significant sex difference in the atd angle but the Southern Nigerians have a significantly higher TRC than those previously reported for the Zulu. This study, contrary to previous studies, suggests that low TRC is not a negroid dermatoglyphic trai

ISSN:0001-5652    

DOI:10.1159/000153175

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

Results are presented on 3 Amerindian populations of interior French Guiana: the Emerillon, the Wayampi and the Wayana. Blood specimens were examined for the red cell antigens A, A1 B, H, M, N, S, s, P1, C, D, E, c, e, C, K, k, Kpa, Kpb, Jsb, Lea, Leb, Lex, Fya, Fyb, Jka, Dia, I, Xga. The frequencies found are within the range of those previously reported in other Amerindian populations, except for the Diego system, where the Dia gene frequencies are among the highest observed.

ISSN:0001-5652    

DOI:10.1159/000153176

出版商:S. Karger AG    

年代:1981

数据来源: Karger